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    Glossarypyrrolidone carboxylic acid

    naturally occurring compound that helps maintain skin moisture

    Pyrrolidone carboxylic acid, also known as PCA, is a naturally occurring compound found in the skin that helps maintain moisture. It is a derivative of the amino acid glutamic acid and is often used in skincare and haircare products for its hydrating properties, as it can attract and retain water effectively.

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      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

      in Research/Science  123 upvotes 2 years ago
      The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.