63 citations
,
January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
62 citations
,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
60 citations
,
July 2014 in “Autophagy” The protein FLCN is involved in cellular cleanup and is regulated by ULK1.
59 citations
,
February 2021 in “Advanced Functional Materials” The silk fibroin-based hydrogel shows promise for treating melanoma and healing infected wounds by killing tumor cells and bacteria, and supporting skin recovery.
58 citations
,
December 2017 in “Journal of The European Academy of Dermatology and Venereology” Microneedling can help stimulate hair growth, especially when used with other treatments, but it's not better than existing therapies.
57 citations
,
March 2024 in “Nano-Micro Letters” The nanoplatform helps heal wounds by balancing bacteria-killing and inflammation-reducing functions.
57 citations
,
January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
57 citations
,
June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
55 citations
,
August 2009 in “Journal of Feline Medicine and Surgery” Cats with adrenal tumors may have both hyperaldosteronism and hyperprogesteronism.
55 citations
,
August 2003 in “Ultrasound in Obstetrics and Gynecology” Ultrasound and color Doppler can help diagnose and decide treatment for early puberty in young girls.
55 citations
,
October 1975 in “Circulation” Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.
52 citations
,
May 2011 in “APOPTOSIS” Hydroxyl radicals cause hair follicle cell death during chemotherapy by reducing Bcl-2 protein levels.
52 citations
,
December 2000 in “Archives of Dermatological Research” Scalp skin barrier affects hair loss; personalized treatments needed.
52 citations
,
October 1999 in “Developmental Dynamics” Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.
50 citations
,
January 2018 in “Acta physiologica” Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
50 citations
,
April 2010 in “Biology direct” Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.
49 citations
,
January 2024 in “Regenerative Biomaterials” The new nanofiber patch speeds up diabetic wound healing and improves healing quality.
49 citations
,
October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
49 citations
,
July 2000 in “Journal of Histochemistry & Cytochemistry” POMC-derived peptides are important for skin functions like immune response and stress management.
48 citations
,
March 2020 in “Stem Cell Research & Therapy” Using a collagen sponge scaffold helps stem cells become more like skin cells.
47 citations
,
August 2024 in “Science Advances” The new sprayable wound mask helps heal wounds without scars.
47 citations
,
September 2023 in “Pharmacological Reports” Vitamins A, B3, C, D, and E can improve skin health and immunity.
46 citations
,
April 2008 in “Archives of Dermatological Research” Substance P may worsen acne by increasing inflammation, but corticosteroids might help by reducing this effect.
45 citations
,
August 2018 in “Journal of Lipid Research” Blocking the ATX-LPA pathway may improve insulin sensitivity and mitochondrial function in obesity.
45 citations
,
August 2010 in “Hormone Molecular Biology and Clinical Investigation” Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.
45 citations
,
December 2006 in “Biopolymers” Permanent waving weakens hair by altering its protein structure.
44 citations
,
September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
44 citations
,
March 2016 in “Frontiers in cellular neuroscience” Some natural compounds can protect fish ear cells from damage by certain antibiotics without affecting the antibiotics' ability to fight infections.
44 citations
,
April 2011 in “Critical reviews in analytical chemistry” Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.