1 citations
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February 2023 in “Russian Journal of Bioorganic Chemistry” The new compound may be a safer alternative to finasteride for prostate protection.
A 14-year-old girl with a condition that makes her hair easy to pull out also has a hair-pulling disorder, and treatment helped but she relapsed after a year.
April 2018 in “The Journal of urology/The journal of urology” A new score can help predict which patients might have trouble urinating after prostate surgery.
14 citations
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October 2015 in “PLoS ONE” Keratin 14 is uniquely found in a specific group of placental cells.
April 2020 in “Journal of the Endocrine Society” A 14-year-old girl with no menstrual period was diagnosed with Swyer Syndrome and treated for a related cancer risk.
April 2017 in “Journal of Investigative Dermatology” Certain mutations in the KLHL24 gene cause a skin disorder by breaking down an important skin protein.
38 citations
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November 1991 in “Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin” Keratins 8 and 14 can help identify and diagnose benign skin tumors.
15 citations
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June 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.
9 citations
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November 2014 in “Indian Journal of Endocrinology and Metabolism” A 15-year-old girl with rare reproductive disorders received hormone therapy to develop secondary sexual traits, but infertility persisted.
June 2026 in “Biomolecules and Biomedicine” This study examined serum levels of phoenixin-14 (PNX-14) and phoenixin-20 (PNX-20) in 90 women with polycystic ovary syndrome (PCOS) compared to 60 healthy controls, finding that both isoforms were significantly elevated in PCOS patients. These isoforms positively correlated with anti-Müllerian hormone (AMH), insulin, and luteinizing hormone (LH), and negatively with sex hormone-binding globulin (SHBG) and high-density lipoprotein (HDL) cholesterol. The study demonstrated moderate diagnostic utility for PNX isoforms, with AUC values of 0.834 for PNX-14 and 0.819 for PNX-20, suggesting their potential role in multi-marker assessment frameworks for PCOS. However, the cross-sectional design limits causal conclusions, necessitating further research to validate these associations.
September 2024 in “Toxicology Letters” Cortisone and cortisol levels in pregnant women’s hair increase as labor approaches, indicating higher stress.
21 citations
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September 2005 in “The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology/Anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology” Caspase-14 is important for skin and hair development in all mammals.
15 citations
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November 2015 in “International Journal of Dermatology” Keratin 14 may be an autoantigen in autoimmune skin diseases.
October 2025 in “Transplantation” Dissolving microneedles can effectively deliver dutasteride for hair loss treatment.
January 2025 in “Pediatrics in Review” The boy's symptoms improved with vitamin C treatment, highlighting the need to consider scurvy in kids with unusual diets.
December 2022 in “Journal of Paediatrics and Child Health” A 14-year-old girl experienced severely itchy lesions in the armpits and pubic region for 6 months, following laser treatment and axillary hair loss. The lesions were skin-coloured to yellowish-brown papules, 1–2 mm in size, with a dome-shaped, smooth surface, distributed around hair follicles. Despite treatment with ketoconazole cream for a suspected fungal infection, there was no improvement. The document did not provide the diagnosis, which was referenced on another page.
January 2001 in “Acta Academiae Medicine Militaris Tertiae” K14 expression in young rats differs from adults.
6 citations
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January 2024 in “ACS Medicinal Chemistry Letters” Cepharanthine and berbamine may affect SK channels, influencing their therapeutic effects.
1 citations
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March 2025 in “Journal of Society of Cosmetic Chemists of Japan” BECD helps straighten wavy hair by reducing undulation.
![[4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide (ISCK03) Inhibits SCF/c-kit Signaling in 501mel Human Melanoma Cells and Abolishes Melanin Production in Mice and Brownish Guinea Pigs](/images/research/4eb017dc-711d-4926-bcd0-c3b8f48e3a99/small/19974.jpg)
26 citations
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July 2007 in “Biochemical Pharmacology” ISCK03 stops melanin production in human melanoma cells and lightens skin color in mice and guinea pigs.
Drinking sweetened tea and late bedtimes increase the risk of hair loss in women.
February 2024 in “Animals” Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.
The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.
January 2023 in “Bioorganičeskaâ himiâ” The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.
7 citations
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January 2019 in “Australasian Journal of Dermatology” A genetic marker linked to a type of hair loss was found in most patients studied.
19 citations
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February 2013 in “Archives of Dermatological Research” 14 citations
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May 2005 in “Steroids” A new method was developed to make finasteride for treating hair loss.
2 citations
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August 2004 Early diagnosis and proper treatment improve outcomes for methylmalonic acidemia.
January 2026 in “Frontiers in Medicine” A child has a rare hair and skin disorder due to specific gene variants, suggesting broader genetic testing is needed.
sFRP4 partially inhibits hair regeneration, but the study needs clearer data analysis and better explanation of the process.