research New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors
New compounds may help treat prostate issues without affecting androgen receptors.
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research Chemical composition and industrial applications of Maritime pine (Pinus pinaster Ait.) bark and other non-wood parts
Maritime pine bark has various chemical components useful for different industrial uses.
research Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research Chrysanthemum species used as food and medicine: Understanding quality differences on the global market
Some Chrysanthemum samples from the USA, Europe, and China differ in quality and some contain harmful cadmium.
research Potential of the Nano-Encapsulation of Antioxidant Molecules in Wound Healing Applications: An Innovative Strategy to Enhance the Bio-Profile
Combining polymers and lipids may improve antioxidant delivery for wound healing, but practical challenges remain.
research Scoparone Induces Expression of Pluripotency Transcription Factors SOX2 and NANOG in Dermal Papilla Cells
Scoparone may help stimulate hair growth by increasing stem cell-related proteins in skin cells.
research Evaluation of Biological Activity Exerted by an Aza-bicyclocarboxylic acid Derivative using Anischemia-Reperfusion Injury Model
Compound 3 protects the heart from damage by activating A1-adenosine receptors.
research Biological Potential and Therapeutic Effectiveness of Hinokiflavone in Medicine: The Effective Components of Herbal Medicines for Treatment of Cancers and Associated Complications
Hinokiflavone may help treat cancers and other health issues.
research A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives
A new, efficient method was developed to synthesize a specific compound and its derivatives.
research A Quantitative Measurement Method for Nuclear-Pleomorphism Scoring in Breast Cancer
A new method accurately measures cell changes in breast cancer.
research The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and across the Skin
Nanovesicles improve drug delivery through the skin, offering better treatment outcomes and fewer side effects.
research Fibronectin Connecting Cell Sheet Based on Click Chemistry for Wound Repair
Fibronectin-attached cell sheets improve wound healing and are safe and effective.
research Isolation and identification of hair growth potential fraction from active plant extract of Blumea eriantha DC grown in Western Ghat of India: In silico study
Blumea eriantha DC extract shows strong potential for promoting hair growth.
research Stabilization of epithelial β-catenin compromises mammary cell fate acquisition and branching morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Potential of Natural Products in Hangeshashinto Water Extract on the Direct Suppression of Stomatitis Induced by Intra-/Extracellular Advanced Glycation End-Products
Hangeshashinto's natural products may help treat stomatitis by reducing inflammation and cytotoxicity.
research Composition, structural features, and multifunctional properties of extracellular polysaccharides from the non-toxic green alga Parachlorella sp.
The green alga Parachlorella sp. has potential for use in cosmetics and health products due to its antioxidant, anti-hypertensive, and hair growth properties.
research Synthesis of a new amino acid derivative with long‐lasting hair shape control effects and elucidation of its mechanisms
A new amino acid derivative, ATS, improves hair texture and moisture, making it easier to straighten curly hair.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research Chemistry, Pharmacology and Therapeutic Potential of Decursin: A Promising Natural Lead for New Drug Discovery and Development
Decursin shows promise for treating cancer, neuroprotection, inflammation, and hair loss.
research Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer
New treatments targeting androgen receptors show promise for drug-resistant prostate cancer.
research Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride
A new method was developed to purify finasteride for better medical use.
research Diphenyl cresyl phosphate [MAK Value Documentations, 2003]
Diphenyl cresyl phosphate has low toxicity but can harm the liver, kidneys, adrenal glands, and testicles at high doses.
research Discovery of an Androgen Receptor Degrader Featuring a Pyridazinyl Glutarimide CRBN-Binding Motif for Transdermal Treatment of Androgenetic Alopecia
dAR-6–1 is a promising new treatment for hair loss that works better than minoxidil.
research Effects of immunosuppressive peptidyl-prolyl cis-trans isomerase (PPIase) inhibitors, cyclosporin A, FK506, ascomycin and rapamycin, on hair growth initiation in mouse: immunosuppression is not required for new hair growth
Cyclosporin A and FK506 can start new hair growth without needing immunosuppression.
research PKCδ/MAPKs and NF-κB Pathways are Involved in the Regulation of Ingenane-Type Diterpenoids from Euphorbia neriifolia on Macrophage Function
Euph E and Euri A from Euphorbia neriifolia help control inflammation and immune response in cells.
research In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus spina-christi
Compounds from Ziziphus spina-christi roots show strong antibacterial and antioxidant potential.
research Isolation, Structural Elucidation and Therapeutic Potentials of Root of Cucurbita pepo
Pumpkin roots contain compounds like Alpha-spinasterol, squalene, and palmitic acid, which may have health benefits like reducing depression, treating certain cancers, and having antibacterial properties.
research Chitin and Chitosans: Characteristics, Eco-Friendly Processes, and Applications in Cosmetic Science
Chitosan is a sustainable, versatile ingredient in cosmetics, enhancing skin hydration and anti-aging while promoting eco-friendly practices.
research State-of-the-Art Review of Electrospun Gelatin-Based Nanofiber Dressings for Wound Healing Applications
Electrospun gelatin-based nanofiber dressings are promising for wound healing due to their effective healing properties and ability to protect against infections.
research LC/MS analysis of stratum corneum lipids: ceramide profiling and discovery
A new, quick method was developed to analyze skin lipids, discovering a new ceramide subclass.