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Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.

Four-amino acid part makes enzyme sensitive to finasteride.

DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.

Dihydrotestosterone specifically binds to hamster sebaceous glands, with a higher affinity than testosterone.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The treatment improved acne, seborrhoea, and hirsutism, with some side effects like spotting and nervousness.

Hormones during puberty increase certain receptors in the brain, and this change is influenced by estrogen levels.

Chronic DHEA supplementation slightly increases testosterone in hair but stays within safe limits.

Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.

17β-Estradiol boosts allergic reactions and slows thymus aging in mice.

Cyproterone acetate is a safe treatment that causes modest feminization in transgender female adolescents, and works better with added estrogens.

DHEA treatment helps grow pubic hair and boosts mood in girls with adrenal issues.

A new compound effectively inhibits human 5α-reductase 1.

Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.

The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

Testosterone and letrozole treatment speeds up puberty in boys with delayed development.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

Mutants of CYP154C2 enzyme significantly improved steroid conversion efficiency.

Using 5-butylpicolinate esters improves the sensitivity and reliability of detecting testosterone and dihydrotestosterone in saliva.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Androgen levels increase with puberty and are linked to sexual hair development.