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17α-Estradiol solution safely improves hair density and thickness in female pattern hair loss.

2-Ethylhexanoic acid harms fertility and delays development in rats.

Some cannabinoid derivatives may be more effective than current drugs at targeting proteins relevant to prostate cancer treatment.

Transgender females can reach their target estrogen levels using estradiol patches, especially if oral treatments fail or if they're at risk for blood clots. Often, the highest dose patch is needed.

SRD5A2 methylation in blood can predict how well someone will respond to finasteride treatment.

Finasteride helps female-pattern hair loss.

Metabolite 7 is a strong inhibitor for Alzheimer's disease management.

The method effectively showed that the two exemestane preparations are bioequivalent.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.

Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.

Mutations at Val-889 and Arg-752 disrupt key interactions in androgen receptor dimerization.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

New compounds may help treat prostate cancer by reducing cell growth.

A new method accurately measures nine neuroactive steroids in small blood samples, helping to study brain diseases.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.

Androstanediol glucuronide is a reliable marker for hirsutism in women.

New progesterone-based compounds can block male hormones.