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Two impurities in finasteride were identified and characterized as cyclohexyl and phenyl analogs.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

A woman's severe male hormone excess was caused by a small, hard-to-find ovarian tumor.

Six months of treatment improved PCOS symptoms and reduced AMH levels.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

A specific metabolite, not a receptor protein, triggers the production of certain kidney enzymes, but this process is disrupted in mice with a mutation causing testicular feminization.

The compound 4c showed strong potential as an anticancer agent.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

A new compound slows cancer cell growth and causes cell death by blocking cell cycle progression and increasing cell-damaging molecules.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The treatment changed hormone levels and increased sexual behavior in female capuchin monkeys.

Some medications can reduce excessive hair growth in women, but more research is needed to find the best treatment combinations.

The β-sitosterol hair gel is effective and promising for treating hair loss.

The topical solution increased hair count but wasn't significantly better than placebo in other measures.

Cyproterone acetate and ethinylestradiol significantly lowered AMH levels in PCOS patients resistant to clomiphene.

New method effectively detects illegal hormones in anti-aging foods.

Neurosteroids play a key role in controlling the brain-adrenal gland activity in pregnant sheep, both in normal and stressful situations.

Clascoterone is a promising topical treatment for hair loss and acne with fewer side effects.

A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.

High doses of norethindrone acetate in rats caused various organ changes but didn't significantly increase tumor rates.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Polysaccharide-based niosomes improve drug delivery and show promise in cancer therapy but face challenges in scalability and stability.

Machine learning improves DNA predictions for eye and hair color, but challenges remain for skin tone and facial features.

Finasteride reduces prostate size and PSA levels in young patients.

Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.