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Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

A new method accurately measures nine steroid hormones in human serum with high sensitivity.

5 Alpha-Reductase Inhibitors reduce the effects of testosterone by blocking its conversion into a stronger form.

Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

Steroid cell tumors in the ovary are rare, can produce testosterone causing symptoms, and are mainly treated with surgery.

Early diagnosis and treatment of PCOS in teenagers can help prevent more severe adult PCOS.

A new mutation in the DCAF17 gene was found to cause Woodhouse-Sakati syndrome in a large family.

A specific gene mutation causes Olmsted syndrome.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Mice without active or present vitamin D receptors maintain normal blood sugar control and islet gene expression when calcium levels are normal.

Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.

Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

Truncating mutations in the C2orf37 gene cause Woodhouse–Sakati syndrome.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

The IRS-2 Asp/Asp genotype may increase the risk of PCOS in Chinese women, especially if they are not obese.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Vitamin D receptor helps prevent skin tumors.

Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

Antiandrogens and finasteride may help treat excess hair and hair loss in women.

Deoxycorticosterone and its metabolites help prevent seizures by interacting with specific receptors.

Females with idiopathic hirsutism have higher levels of omentin-1, which may lead to excessive hair growth.

Hidradenitis suppurativa might be a type of autoinflammatory skin disease.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

About 50% of 46, XY DSD cases lack a genetic diagnosis, but advanced sequencing methods improve detection.

Hirsutism and acne indicate high androgen levels in women with PCOS, suggesting early treatment can help.

Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.

A new compound effectively inhibits human 5α-reductase 1.

MK-386 reduces sebum DHT levels.