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Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.

Human hair follicles can process steroid hormones like DHEA.

Measuring 17-hydroxyprogesterone in hair can help monitor androgen levels in people with congenital adrenal hyperplasia.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.

CYP11A1 is crucial for skin health and disease by producing important steroids.