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Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.

Corneodesmosin is crucial for skin and hair health, and its dysfunction can cause skin and hair disorders.

Different harmful mutations in the CDH3 gene cause HJMD, but symptoms vary among individuals.

Overexpressing NSD3 in mice causes breast cancer-like tumors and gland abnormalities.

The salts have diverse molecular packing with significant hydrogen interactions.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.

DDS treatment for LABD can cause severe side effects like anemia and hair loss, requiring careful monitoring.

The hair follicle dermal sheath is essential for hair shedding and needs to communicate with the outer root sheath for normal hair growth cycles.

A novel CLDN1 mutation in a 2-month-old with NISCH showed improvement with symptom management.

New technologies replicate human skin for testing without animals.

Autoimmune Polyendocrine Syndromes involve specific combinations of endocrine and non-endocrine autoimmune diseases.

XEDAR deficiency prevents muscle degeneration in EDA-A2 transgenic mice.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

Desmoglein 1 can partly make up for the loss of Desmoglein 3 in hair adhesion but not in mucous membranes.

A new mouse mutation causes skin and hair defects due to a gene change.

TTD hair is brittle due to fewer sulfur amino acids and unstable disulfide bonds.

NM2 and RLC phosphorylation are essential for normal inner ear hair cell function.

Researchers found three types of melanocytes in developing mouse skin, each with different genes and locations.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

The most common sign of aging at the gene level is more Ectodysplasin A2 Receptor (EDA2R) being made.

Human-induced stem cell-created skin models can help understand skin diseases by studying the skin's layers.

Three new finasteride solvates found, change forms under different drying conditions.

Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.

Trichothiodystrophy hair is structurally abnormal with protein and organization issues.

Inhibiting ACE2 improves skin regeneration during tissue expansion.