March 2012 in “Journal of Pediatric and Adolescent Gynecology” Doctors vary in how they initially test for PCOS, but most agree on using oral contraceptives and lifestyle changes as first treatments.
25 citations
,
October 2019 in “Journal of Endocrinological Investigation” Both types of oral contraceptives improved symptoms and hormone levels in women with PCOS.
8 citations
,
September 2024 in “Portuguese Journal of Dermatology and Venereology” Early treatment of PCOS is crucial for better health and quality of life.
6 citations
,
April 2018 in “Obstetrics, gynaecology and reproductive medicine” Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.
162 citations
,
January 2015 in “Trends in Endocrinology and Metabolism” Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
3 citations
,
January 2022 in “Anais Brasileiros De Dermatologia” Androgenetic alopecia in teens is linked to obesity and other metabolic risks, needing early diagnosis and management.
122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
4 citations
,
May 2024 in “Steroids” The method accurately measures sex hormones in human plasma but can have small errors.
7 citations
,
January 2018 in “International Journal of Trichology” Taking 5 mg/day finasteride can cause side effects in women with hair loss, but these are usually mild and fade over time, making the treatment beneficial in the long run.
June 2020 in “Medicina estética” More research is needed to find effective treatments for Female Pattern Hair Loss.
June 2020 in “Medicina estética (Madrid)” Female pattern hair loss is common and should be treated early to prevent worsening, with Minoxidil being the main approved treatment.
1 citations
,
March 2005 in “Trends in Endocrinology and Metabolism” Androgens affect behavior, hair, bones, muscles, and the heart, and can be used to treat certain conditions.
January 1983 in “Elsevier eBooks” Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.
January 2020 in “Archives of urology” Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.
54 citations
,
June 1985 in “American Journal of Dermatopathology” Minoxidil helps grow longer, thicker hair in bald scalps of stumptailed macaques, and early treatment is more effective.
3 citations
,
November 1999 in “Journal of Cutaneous Medicine and Surgery” AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.
June 1995 in “International Journal of Gynecology & Obstetrics” Long-term use of oral contraceptives, especially starting before age 20, may increase the risk of early-onset breast cancer.
June 1995 in “International Journal of Gynecology & Obstetrics” Higher doses of oestradiol implants improve bone density in postmenopausal women.
June 1995 in “International Journal of Gynecology & Obstetrics” Cabergoline is more effective and has fewer side effects than bromocriptine for treating women with hyperprolactinemic amenorrhea.
8 citations
,
June 2016 in “Clinical Chemistry” PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
1 citations
,
June 2019 in “Innovare journal of medical sciences” Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.
135 citations
,
March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
14 citations
,
November 1982 in “British Journal of Dermatology” Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
2 citations
,
September 2008 in “Fertility and Sterility” Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.
8 citations
,
October 1998 in “Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology” Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
4 citations
,
January 1989 in “Journal of Steroid Biochemistry” Women with hyperandrogenism have higher androgen levels and lower SHBG, which may contribute to conditions like excessive hair growth and early puberty.
20 citations
,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
1 citations
,
January 2019 in “Elsevier eBooks” Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
72 citations
,
January 2011 in “Current Pharmaceutical Design” S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.
18 citations
,
March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.