research Finasteride blocks progesterone synthesis in MA-10 Leydig tumor cells.
Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
Search
for
Sort by
Research
540-570 / 1000+ results research The antiandrogen cyproterone acetate: discovery, chemistry, basic pharmacology, clinical use and tool in basic research*
research Evaluation of Hair Growth Promoting Activity of Standardized Soybean Extract on Testosterone-Induced Alopecia
Soybean extract may help hair growth in testosterone-related hair loss.
research Assessing tolerability and physiological responses to 17α-estradiol administration in male rhesus macaques
research MK-386, an Inhibitor of 5α-Reductase Type 1, Reduces Dihydrotestosterone Concentrations in Serum and Sebum without Affecting Dihydrotestosterone Concentrations in Semen1
MK-386 lowers DHT in blood and skin but not in semen.
research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men
research 5 Alpha-reductase inhibitors: whatʼs new?
A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.
research 12 Treatment of hirsutism with 5α-reductase inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Effects of In Utero Exposure to D-004, a Lipid Extract from Roystonea regia Fruits, in the Male Rat: A Comparison with Finasteride
D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.
research Diagnosis of hyperandrogenism: Biochemical criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Sexual steroid regulation of spermatogenesis: new actors enter the stage
Estrogens and androgens are crucial for male fertility.
research Synthesis of a 4-azasteroid hormones compound
Finasteride was successfully synthesized from Pregnadienolone acetate.
research Is idiopathic hirsutism idiopathic?
Idiopathic hirsutism may be linked to increased enzyme activity.
research Suppression of spermatogenesis with desogestrel and testosterone pellets is not enhanced by addition of finasteride.
research 193 Unveiling the role of estradiol in the pathogenesis of female pattern hair loss
research Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride
Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
research Luncheon Symposium (LS) : Update on the efficacy and safety of dutasteride in the management of androgenetic alopecia
Dutasteride is effective and safe for treating common hair loss, and it's more potent than finasteride, leading to better hair growth and thickness.
research Studies of androgen metabolism and action in cultured hair and skin cells
Androgens don't directly affect hair cell growth or protein production.
research Pharmacological inhibition of 5α-reductase in androgenetic alopecia: a comparative narrative review of finasteride and dutasteride, with attention to responder heterogeneity and female pattern hair loss
Finasteride and dutasteride effectively treat hair loss, with dutasteride showing slightly better results.
research Pharmacological inhibition of 5α-reductase in androgenetic alopecia: a comparative narrative review of finasteride and dutasteride, with attention to responder heterogeneity and female pattern hair loss
Finasteride and dutasteride effectively treat hair loss, with dutasteride showing slightly better results.
research Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Estrogenic Potential of 2-Alkyl-4-(thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
A substance called Compound 2g can strongly block STS (a hormone-related enzyme) without affecting estrogen levels, making it potentially good for treating breast cancer.
research ST008 Male androgenetic alopecia: A new treatment paradigm
New treatment improves male hair loss.
research Establishing and Verifying a Robust Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Seven Androgens Present in Plasma Samples
The method accurately measures seven androgens in plasma and shows different hormone levels in females with acne and obesity.
research Crystal Structure and Synthesis of 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione
The document explains how to make a compound called 3.BETA.-Benzoyloxy-4-pregnen-16.ALPHA.,17.ALPHA.-epoxy-6,20-dione and describes its crystal structure.
research Dodatek A: Model matematyczny AL/RC/ASE. Functional Androgen Axis (FOA) - wersja operacyjna v1.2
The model improves understanding of androgen interactions by focusing on signal intensity and system capacity.
research Torilin fromTorilis japonica,as a New Inhibitor of Testosterone 5α-Reductase
Torilin from Torilis japonica can inhibit testosterone 5α-reductase but is less effective than finasteride.
research Prescribing testosterone and DHEA: The role of androgens in women
Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
research METABOLISM AND ACTION OF ANDROGEN IN THE SKIN
Androgens affect skin conditions like acne and hair loss through specific biochemical pathways.
research Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study
Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.