Search

everythingexperts & clinicslearnresearchcommunity

for

Search:↓

Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.

DHEA may play a complex role in PCOS, affecting hormones, metabolism, and symptoms.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Men with hair loss don't necessarily have higher levels of the hormone DHEA-S, but this hormone tends to decrease with age.

Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

MK-386 lowers DHT in blood and skin but not in semen.

A 17-year-old female with adrenogenital syndrome produces very high levels of androgens, which prevent complete feminization despite high estrogen doses.

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.

Drospirenone can hide symptoms of certain hormonal disorders, complicating diagnosis.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

A new compound that could treat various androgen-related conditions was created and analyzed.

The antiandrogen 11α-hydroxyprogesterone effectively reduces skin oil and cholesterol when applied to the skin.

DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.

Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.

Adding a specific gene to skin cells can help treat skin disorders like psoriasis.

Certain progesterone derivatives can inhibit enzymes and reduce androgenic activity, potentially affecting prostate growth.

The woman had a genetic condition causing high cortisol and androgen levels, treatable with dexamethasone.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.