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New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

7 citations , October 2024 in “AAPS PharmSciTech”

CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.

Brain Allopregnanolone Induces Marked Scratching Behavior in Diet-Induced Atopic Dermatitis Mouse Model

research Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model

6 citations , February 2019 in “Scientific reports”

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro

5 citations , January 2017 in “Molecular Medicine Reports”

Human hair follicle cells can be turned into neural stem cell-like cells, which might help treat brain diseases.

research Effects of extracellular matrix on the growth characteristics of human dermal papillae cellsin vitro</i>

2 citations , July 2016 in “Clinical and Experimental Dermatology”

Some types of extracellular matrix can change how human skin cells grow but don't affect their basic functions.

research The effects of common house fly (Musca domestica) larvaederived substances on wound healing in mouse model
1 citations , December 2022 in “Parasitologists United Journal”

House fly larvae substances improve wound healing and skin regeneration, especially in immunosuppressed mice.

research Safety and efficacy of actinic keratoses reduction with a 3 day application of ingenol disoxate field treatment to the face, chest and balding scalp
May 2017 in “Journal of The American Academy of Dermatology”

The treatment increased hair follicle counts and is potentially effective for male hair loss without serious side effects.

research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation
120 citations , August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology”

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

research Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin
13 citations , August 2020 in “Frontiers in Cell and Developmental Biology”

Twist1 helps maintain important features of cells crucial for hair growth by working with Tcf4 and β-catenin.

research Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss
5 citations , April 2018 in “Journal of Dermatological Science”

Adjusting estradiol-ANGPT2 levels can promote hair growth in female pattern hair loss.

research Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease
February 2026 in “Journal of Integrative Neuroscience”

NGF-modified hair follicle stem cells may help treat Alzheimer's by improving brain function and reducing harmful proteins.

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischaemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model
June 2022 in “Research Square (Research Square)”

Hair follicle stem cells can help heal intestinal injuries in rats.

research Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non‐depilated mouse model
31 citations , April 2007 in “Experimental Dermatology”

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.

research Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro
24 citations , February 2015 in “Experimental Cell Research”

NFIC helps human dental stem cells grow and become tooth-like cells.

research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems
17 citations , December 2019 in “Stem Cell Research & Therapy”

Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.

research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro</i> evaluation to animal study
14 citations , January 2020 in “Biomaterials Science”

Created microspheres show potential for safe and effective use in prostate artery embolization.

research Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model
3 citations , January 2023 in “PloS one”

Implanting hair-follicle stem cells in mice brains helped repair brain bleeding and reduced brain inflammation.

research Topical treatment with the bacterium-derived c-Met agonist InlB321/15 accelerates healing in the abrasion wound mouse model
3 citations , October 2018 in “Archives of Dermatological Research”

Applying InlB321/15 to wounds sped up healing in mice.

research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model
2 citations , September 2018 in “Tissue Engineering Part A”

Xeno-free three-dimensional stem cell masses are safe and effective for improving blood flow and tissue repair in limb ischemia.

research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro
February 2026 in “Human Cell”

MSC-CM can boost skin cell growth and movement, aiding skin repair.

research Exosome Therapy from Hypoxia-treated Mesenchymal Stem Cells Reduces TNF-α and Increases VEGF Levels in Fluconazole-Induced Alopecia Model
November 2025 in “Molecular and Cellular Biomedical Sciences”

Exosome therapy from treated stem cells may help reduce inflammation and promote hair regrowth in alopecia.

research Secretome of bovine umbilical vein endothelial cells promote wound healing regeneration on the second degree rat model burn injury
January 2023 in “Open veterinary journal”

Cow blood vessel cell secretions helped heal rat burn wounds and may treat burns and hair loss.

research Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness
34 citations , July 2018 in “American Journal of Physiology-heart and Circulatory Physiology”

Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.

research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models
9 citations , April 2021 in “Evidence-based complementary and alternative medicine”

Guilu Erxian Glue may help reduce chemotherapy side effects like weight loss and heart stress.

research Amnion bilayer for dressing and graft replacement for delayed grafting of full-thickness burns; A study in a rat model
3 citations , January 2022 in “PLoS ONE”

The amnion bilayer dressing improved healing and reduced scarring in full-thickness burns.

research Conditioned medium from primary cytotrophoblasts, primary placenta-derived mesenchymal stem cells, or sub-cultured placental tissue promoted HUVECs angiogenesis in vitro
January 2021

Placental cell medium boosts blood vessel growth in lab tests.

research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model
April 2017 in “Journal of Investigative Dermatology”

Triptolide effectively and safely reduces actinic keratosis lesions in mice.

research Involucrin, but not filaggrin and Kdap mRNA, expression is downregulated in 3-D cultures of intact rat hair bulbs after calcium stimulation
3 citations , July 2011 in “Folia Histochemica et Cytobiologica”

Calcium reduces involucrin in rat hair bulbs but doesn't affect filaggrin and Kdap.

research Hair organ regeneration via the bioengineered hair follicular unit transplantation
66 citations , May 2012 in “Scientific Reports”

Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.

research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
19 citations , April 2015 in “Developmental Dynamics”

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

research Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis
January 2026 in “Scientific Reports”

Sesamin may help treat hair loss by affecting specific cell pathways.

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research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

research Brain allopregnanolone induces marked scratching behaviour in diet-induced atopic dermatitis mouse model

research Differentiation of nestin-negative human hair follicle outer root sheath cells into neurons in vitro

research Effects of extracellular matrix on the growth characteristics of human dermal papillae cellsin vitro</i>

research The effects of common house fly (Musca domestica) larvaederived substances on wound healing in mouse model

research Safety and efficacy of actinic keratoses reduction with a 3 day application of ingenol disoxate field treatment to the face, chest and balding scalp

research Markers to Evaluate the Quality and Self-Renewing Potential of Engineered Human Skin Substitutes In Vitro and after Transplantation

research Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin

research Reversal of the hair loss phenotype by modulating the estradiol-ANGPT2 axis in the mouse model of female pattern hair loss

research Therapeutic Potential of Nerve Growth Factor-Modified Hair Follicle Stem Cells Transplantation in a Rat Model of Alzheimer’s Disease

research Transplanted hair follicle mesenchymal stem cells alleviated small intestinal ischaemia–reperfusion injury via intrinsic and paracrine mechanisms in a rat model

research Foot shock stress prolongs the telogen stage of the spontaneous hair cycle in a non‐depilated mouse model

research Nuclear Factor I-C promotes proliferation and differentiation of apical papilla-derived human stem cells in vitro

research Pre-aggregation of scalp progenitor dermal and epidermal stem cells activates the WNT pathway and promotes hair follicle formation in in vitro and in vivo systems

research Development of finasteride/PHBV@polyvinyl alcohol/chitosan reservoir-type microspheres as a potential embolic agent: from in vitro</i> evaluation to animal study

research Direct implantation of hair-follicle-associated pluripotent (HAP) stem cells repairs intracerebral hemorrhage and reduces neuroinflammation in mouse model

research Topical treatment with the bacterium-derived c-Met agonist InlB321/15 accelerates healing in the abrasion wound mouse model

research Therapeutic Effect of a Xeno-Free Three-Dimensional Stem Cell Mass in a Hind Limb Ischemia Model

research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro

research Exosome Therapy from Hypoxia-treated Mesenchymal Stem Cells Reduces TNF-α and Increases VEGF Levels in Fluconazole-Induced Alopecia Model

research Secretome of bovine umbilical vein endothelial cells promote wound healing regeneration on the second degree rat model burn injury

research Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness

research Chinese Herbal Medicine, Guilu Erxian Glue, as Alternative Medicine for Adverse Side Effects of Chemotherapy in Doxorubicin-Treated Cell and Mouse Models

research Amnion bilayer for dressing and graft replacement for delayed grafting of full-thickness burns; A study in a rat model

research Conditioned medium from primary cytotrophoblasts, primary placenta-derived mesenchymal stem cells, or sub-cultured placental tissue promoted HUVECs angiogenesis in vitro

research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model

research Involucrin, but not filaggrin and Kdap mRNA, expression is downregulated in 3-D cultures of intact rat hair bulbs after calcium stimulation

research Hair organ regeneration via the bioengineered hair follicular unit transplantation

research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument

research Sesamin alleviates androgenetic alopecia by targeting the AR MAPK Wnt axis