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Male cells need DHT to respond to testosterone, while female cells do not.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.

A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Variants in the CCDC47 gene are linked to trichohepatoneurodevelopmental syndrome.

Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.

A patient with HAIR-AN syndrome, PCOS, and Hashimoto's thyroiditis improved with early diagnosis and treatment to prevent serious health problems.

Mice without certain skin proteins had abnormal skin and hair development.

Hirsutism, excessive hair growth in women, often caused by high androgen levels and polycystic ovary syndrome, can be treated with medication and weight management.

Evaluate and manage androgen excess in women with a systematic approach, considering both physical and psychological impacts.

A young woman with late-stage Vogt-Koyanagi-Harada disease was successfully treated at a hospital.

A rare ovarian tumor was found in a young woman with a genetic fat disorder.

Hereditary elliptocytosis causes elongated red blood cells and can lead to mild or no symptoms.

A boy and his father with hereditary hypotrichosis simplex were treated for hair loss, but the treatment result is unknown.

Spironolactone helped reduce excessive facial hair in a woman with porphyria cutanea tarda.

Zinc supplements and weaning cured a breast-fed baby's zinc deficiency caused by a gene mutation.

A gene deletion in DSG4 causes sparse hair in some Pakistani families.

A man with a rare lung-focused form of hypereosinophilic syndrome improved with steroid treatment.

A 2-year-old boy was diagnosed with a rare genetic condition causing fragile hair, intellectual issues, and short stature.

VKHD can include rare oral symptoms like discolored teeth.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Women with non-classic congenital adrenal hyperplasia have higher risk for heart and metabolic problems.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.

Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.

A man with a rare disease experienced late hair whitening and loss, but hair color returned, suggesting a good outlook.