10 citations
,
June 2010 in “Expert Opinion on Drug Metabolism & Toxicology” Finasteride reduces prostate cancer risk but may increase high-grade cancer chances.
10 citations
,
May 2010 in “Analytica Chimica Acta” New tests detect finasteride and dutasteride in urine quickly and easily.
9 citations
,
November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
7 citations
,
April 2006 in “Experimental Neurology” Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.
6 citations
,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
4 citations
,
January 2013 in “Dissolution Technologies” A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.
3 citations
,
October 1995 in “International Journal of Dermatology” Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
2 citations
,
December 2013 in “Xenobiotica” Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.
January 2019 in “Arabian Journal of Chemistry” Method found to accurately identify finasteride impurities using liquid chromatography.
19 citations
,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
2 citations
,
October 2004 in “Organic Process Research & Development” The document reviews 20 U.S. patents from July and August 2004 about new drug forms, cancer treatments, aroma chemicals, statin drugs, and various chemical production methods.
59 citations
,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
56 citations
,
January 2007 in “Pharmaceutical Development and Technology” Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
45 citations
,
January 2008 in “Drugs” Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
45 citations
,
February 2005 in “Steroids” Four new compounds were more effective than finasteride in treating prostate issues and hair loss, with one being 100 times more active and safe for use.
39 citations
,
April 2007 in “Therapeutic Drug Monitoring” Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
32 citations
,
July 1999 in “Fertility and Sterility” Finasteride and flutamide both reduce hair growth, but finasteride has fewer side effects.
30 citations
,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
27 citations
,
August 2018 in “Therapeutic Delivery” Nanotechnology could make hair loss treatments more effective and reduce side effects, but more research is needed before it's available.
25 citations
,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
23 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
18 citations
,
April 2010 in “Journal of Chromatography B” New method measures finasteride in blood quickly and accurately.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
11 citations
,
September 2008 in “European Journal of Drug Metabolism and Pharmacokinetics” Finasteride helps reduce pain and inflammation in animals.
10 citations
,
December 2008 in “Journal of Clinical Neuromuscular Disease” Finasteride can cause muscle pain and high creatine kinase levels, but stopping the medication may resolve symptoms.
9 citations
,
October 1993 in “The Journal of Clinical Pharmacology” Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.
7 citations
,
October 2009 in “Journal of the American Geriatrics Society” Finasteride may help reduce inappropriate sexual behaviors in dementia patients with prostate issues.
6 citations
,
March 2018 in “Journal of Chromatography A” New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
5 citations
,
April 2011 in “Bioorganic & Medicinal Chemistry Letters” New Finasteride conjugate improves prostate treatment and vital signs in rats.
1 citations
,
January 2017 in “Asian Journal of Chemistry” New method effectively analyzes finasteride and its stability.