research Production of biologically active oxidized derivatives of finasteride through metabolism byAspergillus nigerculture
Aspergillus niger culture creates two finasteride derivatives with enzyme-inhibiting effects.
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research Isolation and Structural Characterization of Finasteride Degradation Products by Preparative HPLC, HRMS, and NMR
Finasteride breaks down into new compounds under acidic conditions.
research Analytical methods of dutasteride: An overview
Dutasteride is more effective than finasteride for hair loss treatment.
research Analytical Techniques for the Quantification of Finasteride - A Review
Different methods accurately measure Finasteride in medicines and body fluids.
research In Search of Predictive Models for Inhibitors of 5-alpha Reductase 2 Based on the Integration of Bioactivity and Molecular Descriptors Data.
The models can help find better inhibitors for conditions like baldness and prostate disorders.
research Chemical examination of three Indian medicinal plants and their hair growth evaluation studies
Three Indian medicinal plant compounds help hair growth.
research VIBRATIONAL SPECTROSCOPIC INVESTIGATION AND MOLECULAR STRUCTURE OF A 5α-REDUCTASE INHIBITOR: FINASTERIDE
The PW91 method is best for calculating the basic physical and chemical properties of Finasteride, a drug used for prostate issues and hair loss.
research Stability Study of Finasteride: Stability-Indicating LC Method, In Silico and LC–ESI-MS Analysis of Major Degradation Product, and an In Vitro Biological Safety Study
Finasteride's stability and safety confirmed through precise analytical methods.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract ofQuercus acutissimaCortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research A Multi-Technique Approach to the Study of Structural Stability and Desolvation of Two Unusual Channel Hydrate Solvates of Finasteride
Desolvation of finasteride depends on environment and technique.
research Finasteride Blocks the Reduction in Ictal Activity Produced by Exogenous Estrous Cyclicity
research The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness.
Finasteride reduces scalp DHT levels, potentially treating male pattern baldness.
research Regulatory roles of androgens in cutaneous wound healing
Testosterone may slow down wound healing and increase inflammation.
research Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: Potential role of endogenous neurosteroids?
Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.
research Association of Benign Prostatic Hyperplasia with Male Pattern Baldness
Men with enlarged prostates often have more severe baldness.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research Hair loss and herbs for treatment
Herbs can potentially treat hair loss by inhibiting a key enzyme and promoting hair growth, and deficiencies in zinc, biotin, and iron are linked to hair loss.
research Novel agents for the treatment of alopecia
New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
research Finasteride is the main inhibitor of 5α-reductase activity in microdissected dermal papillae of human hair follicles
Finasteride potentially treats hair loss by reducing DHT production.
research Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in the Male
Benign Prostatic Hyperplasia may be caused by changes in how the body processes male hormones.
research Chemical Mechanism of the Covalent Modification of 5.alpha.-Reductases by Finasteride as Probed by Secondary Tritium Isotope Effects
Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
research Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Neonatal finasteride administration decreases dopamine release in nucleus accumbens after alcohol and food presentation in adult male rats
Finasteride given to baby rats reduces dopamine release and increases alcohol consumption in adult males.
research Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators
The study created a new method to test drugs that affect hormone processing in skin.
research Reaction of Finasteride Intermediate with Benzeneseleninic Anhydride: An In-Depth Study
Impure benzeneseleninic anhydride samples cause lower finasteride intermediate yields.
research RP-HPLC Technique for Dustasteride Quantitative Estimation in Tablet Dosage Form: Formulation and Validation of Analytical Technique
A reliable method was developed to measure dutasteride in tablets accurately and consistently.
research Antiandrogens and Androgen Inhibitors
Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.
research P368 Rare skin disorders in IBD patients treated with anti-TNFs
Some IBD patients on anti-TNFs developed severe skin issues, but ustekinumab helped.
research A Case of Azathioprine Induced Severe Myelosuppression and Alopecia Totalis in IgA Nephropathy
Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.