309 citations
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June 2001 in “Molecular and Cellular Endocrinology” Mutations in the androgen receptor gene cause androgen insensitivity, leading to female traits in genetically male individuals.
104 citations
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December 2004 in “Journal of Neurochemistry” Androgens help motor neurons grow by increasing neuritin.
29 citations
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January 1998 in “Dermatology” Many acne patients have high androgen levels, which may lead to PCOD, but treatments like oral contraceptives and antiandrogens can help.
24 citations
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July 2016 in “Steroids” Progesterone and testosterone protect brain cells from damage through specific pathways.
19 citations
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April 2018 in “Clinical cardiology” Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.
11 citations
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February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
9 citations
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February 2004 in “Veterinary Dermatology” Canine hair follicle cells metabolize DHEA and testosterone differently than human cells.
March 2025 in “Journal of Endocrinology and Metabolism” Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.
January 2025 in “International Journal of Molecular Sciences” Fenugreek extract may help treat benign prostatic hyperplasia.
January 2025 in “Case Reports in Genetics” A rare gene variant causes sexual development issues in siblings, needing personalized treatment.
January 2025 in “International Journal of Pharmaceutical Research and Applications” PCOS causes hormonal imbalance, leading to symptoms like irregular periods and infertility.
August 2019 in “Chin J Naut Med & Hyperbar Med” Hyperbaric oxygen therapy improves hair growth and quality of life in androgenic alopecia patients.
4 citations
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August 2021 in “Annals of Translational Medicine” Dihydroartemisinin helps reduce prostate enlargement in rats by stopping the growth of prostate cells.
165 citations
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December 2002 in “Molecular and Cellular Endocrinology” Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
111 citations
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May 2001 in “Human reproduction update” Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” A new gene, JMJD1C, may affect testosterone levels in men.
66 citations
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August 2007 in “Applied and environmental microbiology” The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.
39 citations
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March 2009 in “Archives of Dermatological Research” Apigenin may help promote hair growth and could treat hair loss.
20 citations
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January 2004 in “PubMed Central” 5α-reductase inhibitors like finasteride and dutasteride effectively treat BPH by reducing DHT levels.
11 citations
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September 2021 in “Journal of molecular endocrinology” ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.
11 citations
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May 1990 in “Journal of Dermatological Science” Diazoxide applied to the skin can increase hair growth without harmful side effects.
9 citations
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December 2021 in “Androgens” Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.
9 citations
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March 1985 in “Head & Neck Surgery” Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.
5 citations
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January 2010 in “Acta Chirurgica Iugoslavica” Higher urethral PSA levels after prostate removal may be linked to more scalp hair loss and more PSA in urethral glands.
4 citations
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March 2019 in “JAT. Journal of applied toxicology/Journal of applied toxicology” PFOS exposure disrupts hormone levels and enzyme activities in juvenile frogs, affecting males and females differently.
4 citations
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February 2019 in “PubMed” Clascoterone may be an effective topical treatment for hair loss.
3 citations
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May 2021 in “Dermatologic Clinics” The document concludes that more research is needed to understand hair loss in men and to find new treatments.
2 citations
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April 2007 in “Journal of Labelled Compounds and Radiopharmaceuticals” The conclusion is that tritium-labeled testosterone metabolites can be made and are better converted into dihydrotestosterone in skin cells than in prostate tissue.
1 citations
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January 2018 in “Journal of Cosmetics, Dermatological Sciences and Applications” Ostrich antibodies helped regrow hair in men with hair loss, but the application needs to be easier.
1 citations
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January 2008 in “Actas Dermo-Sifiliográficas” Treat hair loss in postmenopausal women with diet, avoiding certain drugs, and using medications like minoxidil or finasteride.