research Platelet-rich plasma and topical minoxidil 5% in the treatment of severe alopecia areata: Report of two cases
Combining platelet-rich plasma and minoxidil can effectively regrow hair in severe alopecia areata cases.
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research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Sexual effects data lacking on 5-ARI for hair loss
There's not enough data on finasteride's sexual side effects.
research Topical minoxidil solution (1% and 5%) in the treatment of alopecia areata
Minoxidil solution helps hair regrowth in alopecia areata, with 5% being more effective.
research The effects of garlic topical gel (5%) in the treatment of alopecia areata
Garlic gel can help hair grow in people with alopecia areata.
research 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG) from Polygonum multiflorum Thunb.: A Systematic Review on Anti-Aging
TSG from Polygonum multiflorum may help with anti-aging by protecting the brain, heart, bones, and hair.
research A Convenient Synthesis of (16S,20S)-3β-Hydroxy-5α-pregnane-20,16-carbolactam and Its N-alkyl Derivatives
A new, efficient method was developed to synthesize a specific compound and its derivatives.
research Inibição seletiva da 5α-redutase e preservação da aromatase no transplante capilar
A balanced approach using dutasteride and Serenoa repens can improve hair transplant success by protecting follicles and minimizing side effects.
research Pharmacological Role and Clinical Applications of 5α-Reductase Inhibitors-Review Article for Pharmacists and Healthcare Professionals
5α-reductase inhibitors effectively treat enlarged prostate and hair loss but require careful use due to possible side effects.
research A high-performance liquid chromatography–tandem mass spectrometry assay of the androgenic neurosteroid 3α-androstanediol (5α-androstane-3α,17β-diol) in plasma
Testosterone increases 3α-androstanediol levels, which can be blocked by finasteride.
research Expression of AR, 5αR1 and 5αR2 in bladder urothelial carcinoma and relationship to clinicopathological factors
Androgens may influence bladder cancer progression by affecting cellular behavior.
research Alopecia Areata: Good Response to Treatment with Fractional Laser in 5 Cases
Fractional laser treatment helped hair regrowth in patients with alopecia areata.
research Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open‐Label Single‐Arm Clinical Trial
5% topical minoxidil may help reduce hair loss and increase hair growth in telogen effluvium.
research The Effectiveness and Safety of Three Treatment Regimens of Topical Minoxidil 5.0%, Betamethasone 0.064% w/w, and Castor and Jojoba Oils for Alopecia Areata: A Multicenter Cohort Study
Minoxidil with betamethasone is the most effective for hair regrowth in alopecia areata.
research Platelet-Rich Plasma Applications, The Past 5 Years: A Review Article
PRP can reduce pain and improve function, but more standardized research is needed.
research Comparison of the Efficacy and Safety of Topical 5% Minoxidil Solution Alone and in Combination with 0.05% Betamethasone Dipropionate Cream in the Treatment of Alopecia Areata
The combination of minoxidil and betamethasone is more effective for hair regrowth than minoxidil alone.
research Comparative study between topical methotrexate 1% gel and minoxidil 5% gel in the treatment of localized alopecia areata
Minoxidil showed better improvement than methotrexate in treating localized alopecia areata.
research mRNA Levels of Aromatase, 5α-Reductase Isozymes, and Prostate Cancer-Related Genes in Plucked Hair from Young Men with Androgenic Alopecia
Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
research Baricitinib Provides Sustained, Long-Term Efficacy With Consistent Safety for Up to 5 Years of Treatment in Adults With Severe Alopecia Areata: Final Results From BRAVE-AA1 and BRAVE-AA2
Baricitinib is effective and safe for treating severe alopecia areata for up to 5 years.
research Comparison of Therapeutic Efficacy of Topical Tacrolimus 0.1% and Topical Dithranol 0.5% in Treatment of Alopecia Areata
Dithranol is more effective than Tacrolimus for hair regrowth in alopecia areata.
research Comparative study of efficacy of excimer light therapy vs. intralesional triamcinolone vs. topical 5% minoxidil for alopecia areata: an observational study
Intralesional triamcinolone is the most effective treatment for alopecia areata, followed by excimer light therapy, and then topical minoxidil. The scalp responds better to treatment than the beard area.
research Kasus eyebrow alopesia areata yang diterapi dengan kombinasi sekretom, minoxidil 5% topikal dan kortikosteroid topikal
Combining secretome with other treatments quickly improves eyebrow hair growth in alopecia areata.
research 63532 Impact of Eyebrow and Eyelash Hair Loss on Health-Related Quality of Life Among Patients with Alopecia Areata: Results From a Real-World Survey in 5 European Countries
Eyebrow and eyelash hair loss in alopecia areata worsens quality of life.
research Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors
Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.
research Synthesis, Anticancer and Molecular Docking Studies of 2-(4-chlorophenyl)-5-aryl-1,3,4-Oxadiazole Analogues
The compound 4c showed strong potential as an anticancer agent.
![Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear](/images/research/861159f1-7bd4-420c-a16b-4829458efe68/small/15592.jpg)
research Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche.
The compounds tested could potentially treat hair loss and alopecia.
research Comparing the frequency of isotretinoin-induced hair loss at <0.5-mg/kg/d versus ≥0.5-mg/kg/d dosing in acne patients: A systematic review
Higher doses of isotretinoin may lead to more hair loss.
research Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove Oil 10% Topical Minoxidil 5% <u>Research Article</u>Journal of the Faculty of Medicine BaghdadPrint ISSN: 0041-9419, Online ISSN: 2410-8057DOI: https://doi.org/10.32007/jfacmedbaghdad2977. Hair Growth Stimulation in Testosterone-Induced Alopecic Mice: A Comparative Study between Topical Clove oil 10% Topical Minoxidil 5%
Clove oil may help hair growth like minoxidil, but more human tests are needed.
research Referee report. For: Pathogenesis of Androgenetic alopecia [v1; indexed, http://f1000r.es/5ar]
Androgenetic alopecia may be irreversible due to the detachment of a muscle from hair follicles.