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research Antiandrogenic activity of Riboflavin 5′-phosphate (FMN) in 22Rv1 and LNCaP human prostate cancer cell lines

1 citations , January 2022 in “European Journal of Pharmacology”

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

research Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects

April 2026 in “World Allergy Organization Journal”

Allergic rhinitis increases hair loss risk, but antihistamines can reduce it.

research Risks for metabolic syndrome and cardiovascular diseases in both male and female patients with androgenetic alopecia

July 2015 in “Egyptian Journal of Dermatology and Venereology”

People with androgenetic alopecia, both men and women, are more likely to develop heart diseases in the future.

research The synthesis of (−)-4-methyl-8-chloro-trans-1,2,3,4,4a,5,6,10b-octahydrobenzo-[f]-quinolin-3-one-[3-14C] (LY300502-14C]) via a circuitous route

3 citations , October 1994 in “Journal of Labelled Compounds and Radiopharmaceuticals”

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

research Successful treatment of generalized discoid lupus erythematosus with imiquimod cream 5%: a case report and review of the literature.

24 citations , January 2014 in “PubMed”

Imiquimod cream 5% effectively treated generalized discoid lupus erythematosus.

Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-Rich Plasma as a Substitute for Fetal Bovine Serum

research Expansion of Human Dermal Papilla Cells for Clinical Applications Using Human Platelet-rich Plasma as a Substitute for Fetal Bovine Serum

January 2024 in “International Journal of Trichology”

Human platelet-rich plasma is better than fetal bovine serum for growing cells that help hair regrow.

research Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair

37 citations , May 2021 in “Frontiers in Cell and Developmental Biology”

Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.

research Sculpting with stiffness: rigidity as a regulator of morphogenesis

13 citations , April 2023 in “Biochemical Society Transactions”

Tissue stiffness helps shape how organisms develop.

Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice

research Pinus thunbergiii> bark extract rich in flavonoids promotes hair growth in dorsal skin by regulating inflammatory cytokines and increasing growth factors in mice

5 citations , January 2022 in “Molecular Medicine Reports”

Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.

research Post-acute COVID-19 symptom risk in hospitalized and non-hospitalized COVID-19 survivors: A systematic review and meta-analysis
34 citations , February 2023 in “Frontiers in Public Health”

Hospitalized COVID-19 survivors have a higher risk of long-term symptoms and need special care.

research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant
6 citations , June 2012 in “PloS one”

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

research In vitro and In vivo Effects of 17β-N-(4-phenylcarbamoyl) androst-4-en-3- one Derivatives as 5a-reductase Inhibitors on Androgen-dependent Glands
September 2020 in “Current Enzyme Inhibition”

Three compounds were found to inhibit a prostate disease-related enzyme and reduce prostate size more effectively than the current treatment, suggesting they could be used for treating benign prostatic hyperplasia.

research Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche.
10 citations , August 1998 in “Journal of Investigative Dermatology”

The compounds tested could potentially treat hair loss and alopecia.

research The Benefits of Dual Inhibition of 5α Reductase
4 citations , September 2006 in “European Urology Supplements”

Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.

research Physical attractiveness, same-sex stimuli, and male venture capitalists’ financial risk-taking
1 citations , January 2024 in “Frontiers in Psychology”

Less attractive male venture capitalists take more risks influenced by entrepreneurs' looks, while more attractive ones are generally risk-tolerant.

research Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells
January 2026 in “Applied Biological Chemistry”

Ishophloroglucin A from Ishige okamurae may be a natural alternative for treating hair loss by inhibiting 5α-reductase and promoting hair growth.

research The Success of Thread-embedding Therapy in Generating Hair Re-growth in Mice Points to Its Possibly Having a Similar Effect in Humans
20 citations , December 2015 in “Journal of Pharmacopuncture”

Thread-embedding therapy helped hair grow back in mice and might do the same in humans.

research Effects of Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose on androgenic alopecia via inhibiting 5a-reductase and regulating Wnt/β-catenin pathway
July 2024 in “Fitoterapia”

Camellia oleifera seed shell polyphenols and 1,3,6-tri-O-galloylglucose can help treat hair loss by reducing certain hormones and promoting hair growth.

research Author response: The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome
April 2016

Defective protein folding due to a mutation is key in ANE syndrome.

research Decision letter: The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome
April 2016

ANE syndrome is caused by a mutation in the RBM28 protein that disrupts ribosome assembly.

research Atroposelective Synthesis of Biaryl Ni>‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic Ni>‐Oxide Ring Formation
6 citations , August 2024 in “Advanced Science”

A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.

research Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids
8 citations , June 2020 in “The Journal of Clinical Endocrinology and Metabolism”

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

research 5α-Reductase Inhibition Prevents the Luteal Phase Increase in Plasma Allopregnanolone Levels and Mitigates Symptoms in Women with Premenstrual Dysphoric Disorder
110 citations , August 2015 in “Neuropsychopharmacology”

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee
49 citations , February 2019 in “The Journal of Clinical Endocrinology and Metabolism”

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

research 5α-Reductase Inhibitors, Chemical and Clinical Models
17 citations , May 1998 in “Steroids”

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

research Assessment of the Ability of the ChatGPT-5 Model to Pass the Endocrinology Specialization Exam
1 citations , September 2025 in “Cureus”

ChatGPT-5 can pass the endocrinology exam but isn't fully reliable for clinical decisions yet.

research 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid
22 citations , August 2011 in “Journal of Supercritical Fluids”

Rice bran extract might help prevent hair loss.

research The Journey of Platelet Concentrates: An Era of Regeneration in Medicine and Dentistry: A Review
May 2022 in “Acta scientific dental sciences”

Platelet concentrates are useful for tissue repair in medicine and dentistry, with L-PRF showing promising results in various treatments.

research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase
5 citations , February 1997 in “Bioorganic & Medicinal Chemistry”

New compounds were made that effectively block a specific enzyme related to androgen conditions.

research DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data
158 citations , January 2015 in “Artificial Intelligence in Medicine”

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

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