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Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Steroid 5α-reductase evolved from protists and diversified in eukaryotes, with specific roles in mammals and plants.

Anabolic androgenic steroids can increase cancer risk and disrupt hormones.

Finasteride helps protect brain in old male rats.

Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.

Finasteride affects alcohol intake in male mice, possibly due to neurosteroids.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Finasteride lowers cortisol and raises testosterone levels in rats.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Sex hormones affect brain injury differently in males and females.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride helps brain function in rats with liver-related brain issues.

Finasteride can cause serious mental health issues, so it's advised to avoid it for hair loss.

Neurosteroids like neuro-estrogen and neuro-androgen are crucial for brain function and can improve cognition and protect against aging-related decline.

Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.

Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.

Borneol Essential Oil could be a natural and safe acne treatment.

Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.

Certain natural compounds called terpenes may help prevent prostate cancer.

Dutasteride helps reduce heavy drinking, especially for those who drink to cope.

Finasteride reduced seizures and prevented cognitive issues in rats after neonatal asphyxia but increased anxiety later.

Allopregnanolone may help reduce inflammation and symptoms related to post-finasteride syndrome.

Neurosteroids and benzodiazepines reduce neuron excitability, with lasting effects on inhibitory neurons.

Finasteride and dutasteride may cause depression and anxiety, especially in younger men.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.