research Modulating testosterone pathway: a new strategy to tackle male skin aging?
Honokiol might help reduce male skin aging by maintaining testosterone levels.
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60-90 / 1000+ results research Estranys matins de febrer: Pauline Fondevila
Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.
research 5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by supercritical carbon dioxide fluid
Rice bran extract might help prevent hair loss.
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles
Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
research Androgenetische Alopezie beim Mann . Male androgenetic alopecia
Male androgenetic alopecia involves hair follicle miniaturization due to DHT, with potential treatments using inhibitors and blockers.
research The Biomolecular Effects of Finasteride on Male Rat Brain during Administration and after Discontinuation
Finasteride temporarily suppresses brain activity, but some effects last even after stopping.
research The effect of finasteride on the male rat brain
Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.
research Androgen levels and apoptosis in the testis during postnatal development of finasteride-treated male rat offspring
Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
research Management of male pattern hair loss.
Finasteride helps manage male hair loss, but realistic expectations and support are crucial.
research Sexual difference, identification and object choice in individuals with sex differentiation disorders
Gender identity doesn't determine who people are attracted to or their sexual practices.
research Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia
Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
research IMPLICAÇÕES DA TOMA CRÓNICA DA FINASTERIDE PARA A ALOPÉCIA ANDROGENÉTICA NO CARCINOMA DA PRÓSTATA
Chronic use of 1 mg/day finasteride for hair loss may delay prostate cancer diagnosis by lowering PSA levels.
research Male-pattern hair loss: Comprehensive identification of the associated genes as a basis for understanding pathophysiology
Male-pattern hair loss is largely influenced by genetics, with key genes identified.
research Resequencing Analyses Revealed Genetic Diversity and Selection Signatures during Rabbit Breeding and Improvement
Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.
research Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin
Sebocytes play a key role in controlling androgen levels in human skin.
research 5-Alpha-Reductase Inhibitors and Combination Therapy
Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.
research Discriminating in favour of or against men with increased risk of finasteride-related side effects?
Finasteride treats baldness but may cause lasting sexual side effects.
research Comment on: The Gabrin sign
The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.
research Effect of Ficus carica leaf extract on the gene expression of selected factors in HaCaT cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research Reply by the authors
Dutasteride may help prevent prostate cancer, but more research is needed.
research Enzymology of the hair follicle.
Hair follicles convert androgens, affecting hair loss patterns.
research Effect of Sparasis crispa Extract on 5α-Reductase Gene in Dermal Papilla Cells
Cauliflower Mushroom extract may help treat male hair loss by affecting hair growth-related genes.
research Male pattern hair loss: prevention rather than regrowth
Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.
research Genetic and other epidemiological risk factors of infants and children with hypospadias: a case control study
Older parental age, rural living, and specific genetic mutations increase hypospadias risk in children.
research Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1
Male cells need DHT to respond to testosterone, while female cells do not.
research The influence of low dose finasteride, a type II 5α-reductase inhibitor, on circulating neuroactive steroids
Low dose finasteride decreases certain steroids, possibly increasing depression risk.
research Efficacy of an Oral Ageratum Conyzoides Formulation on Increasing Hair Growth and Decreasing Hair Loss in Males and Females: A Randomised Double-Blind Placebo-Controlled Study
Ageratum Conyzoides, when taken orally, can effectively reduce hair loss and improve hair growth.
research Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Effect of MK-386, a novel inhibitor of type 1 5 alpha-reductase, alone and in combination with finasteride, on serum dihydrotestosterone concentrations in men.
MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.