Search for 5ap in research

Progesterone-Induced Stimulation of Mammary Tumorigenesis Is Due to the Progesterone Metabolite, 5α-Dihydroprogesterone (5αP), and Can Be Suppressed by the 5α-Reductase Inhibitor, Finasteride

research Progesterone-induced stimulation of mammary tumorigenesis is due to the progesterone metabolite, 5α-dihydroprogesterone (5αP) and can be suppressed by the 5α-reductase inhibitor, finasteride

21 citations , January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology”

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

research Oligomeric Procyanidins in Apple Polyphenol Are Main Active Components for Inhibition of Pancreatic Lipase and Triglyceride Absorption

282 citations , April 2007 in “Journal of Agricultural and Food Chemistry”

Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.

research Allopregnanolone mediates the exacerbation of Tourette-like responses by acute stress in mouse models

25 citations , June 2017 in “Scientific reports”

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

research Minoxidil Stimulates Elastin Expression in Aortic Smooth Muscle Cells

33 citations , November 1994 in “Archives of Biochemistry and Biophysics”

research Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells

25 citations , January 2017 in “Steroids”

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

research Dermatologist‐diagnosed skin diseases among immigrant Latino poultry processors and other manual workers in North Carolina, USA

16 citations , March 2013 in “International Journal of Dermatology”

Immigrant Latino workers in North Carolina, especially in poultry processing, often have skin diseases like fungal infections and acne.

research Alkaline Phosphatase–Regulated C–C Motif Chemokine Ligand 5 (CCL5) Functions as a Critical Mediator of Hair Follicle Neogenesis

March 2026 in “Tissue Engineering and Regenerative Medicine”

research 5 alpha-reductase and finasteride in pattern alopecia and acne.

2 citations , December 2004 in “PubMed”

research 5alpha-reductase inhibitors/finasteride.

4 citations , January 1996 in “PubMed”

research 5α-Reductase inhibitors in androgenetic alopecia

January 2015 in “Current Opinion in Endocrinology, Diabetes and Obesity”

research 5ARI and PSA: open questions

July 2014 in “Urologia Journal”

5ARI treatment improves PSA test accuracy for prostate cancer diagnosis.

CCL5 Affects the Hair-Inductive Capacity of Three-Dimensional Cultured Dermal Papilla Cells

research 854 CCL5 affects the hair-inductive capacity of three-dimensional (3D)-cultured dermal papilla cells

1 citations , April 2017 in “Journal of Investigative Dermatology”

CCL5 is important for the hair growth potential of human dermal papilla cells.

research Specific inhibition of FGF5-induced cell proliferation by RNA aptamers

15 citations , February 2021 in “Scientific Reports”

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

research Identification and Characterization of a Novel Lysophosphatidic Acid Receptor, p2y5/LPA6

253 citations , April 2009 in “Journal of Biological Chemistry”

p2y5, now called LPA6, is a receptor important for human hair growth.

research Expression of novel keratin associated protein 5 genes in the cuticle layer of human hair follicles

6 citations , April 2005 in “Journal of dermatological science”

The study found nine new hair protein genes in human hair follicles.

research Antipsychotic-Like Properties of 5-α-Reductase Inhibitors

64 citations , March 2008 in “Neuropsychopharmacology”

research Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance

12 citations , March 2021 in “Journal of Investigative Dermatology”

TRPM5 is crucial for maintaining hair growth.

research P25 ELF5 regulation of normal skin development and homeostasis

January 2026 in “British Journal of Dermatology”

ELF5 is essential for skin cell growth and maintenance.

research 5α-reductase isoenzymes mediate stress-exacerbated Tourette-like responses in animal models

May 2018 in “KU ScholarWorks (The University of Kansas)”

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

research A New Look at the 5á-Reductase Inhibitor Finasteride

January 2006

Finasteride, a medication, is being re-evaluated for its effects and uses.

research 5α-Reductases in Human Physiology: An Unfolding Story

November 2012 in “Endocrine Practice”

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

research STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction

32 citations , April 2016 in “Journal of Investigative Dermatology”

STAT5 activation is crucial for starting the hair growth phase.

research Discovery of a transdermally deliverable pentapeptide for activating AdipoR1 to promote hair growth

8 citations , September 2021 in “EMBO Molecular Medicine”

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

research Allopregnanolone is required for prepulse inhibition deficits induced by D1 dopamine receptor activation

12 citations , June 2019 in “Psychoneuroendocrinology”

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

research Finasteride and the 5-Alpha Reductase Inhibitors

October 2025 in “CRC Press eBooks”

STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction, Hair Follicle Regeneration, and Wound Healing

research 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing

1 citations , August 2016 in “Journal of Investigative Dermatology”

Activating STAT5 in the skin's dermal papilla is key for starting hair growth, regenerating hair follicles, and healing wounds.

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