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Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Dermal EZH2 controls skin cell growth and differentiation in mice.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, and antioxidants may help treat hair loss.

The enzyme pyruvate kinase M2 helps hair regrowth and could be a potential treatment for hair loss.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

ELF5 is essential for skin cell growth and maintenance.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

Longer TA repeats in the SRD5A2 gene may increase acne risk in Chinese people.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

Reactive oxygen species (ROS) influence hair growth by causing DNA damage, cell death, and changes in immune cells.

Genetic variations may affect how well finasteride works for BPH patients.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.

2-Methoxyestradiol causes cancer cell death by activating specific pathways, but androgens can block this effect.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Lack of a key enzyme causes severe skin issues and death in mice.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

5αR inhibitors help slow early prostate cancer cell growth, suggesting combined treatments are needed.

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Dock5 is important for skin healing and could help treat diabetic wounds.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

The PIP5K1A gene helps cashmere growth in goats by promoting cell proliferation, and melatonin boosts its expression.

Newly designed proteins can effectively degrade specific proteins in cells, offering a potential new therapy method.

Two specific genes are more active during hair growth in mice.

The study found that in Eclipta prostrata roots, coumestans come from acetate and shikimate pathways, and phenylpropanoid is made only through the shikimate pathway.

Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.