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LGR5 mainly stays inside cells, moving to the trans-Golgi network, and this process is important for its role in cell signaling.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Ceramide synthase 4 is essential for maintaining skin barrier health.

Knocking out the FGF5 gene in sheep increased wool production and hair-follicle density.

ROR2 is crucial for hair follicle stem cell maintenance and self-renewal.

PRC2 is not essential for hair follicle stem cell maintenance or hair growth.

The gene LRRC15 is more active in balding areas of the scalp compared to non-balding areas.

Tet2 and Tet3 enzymes are important for controlling hair growth and shape by affecting gene activity and DNA structure in hair follicles.

Targeting FGF5 could help treat prostate cancer.

Patients with the same vitamin D receptor mutation showed different symptoms due to other factors.

The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

A specific gene mutation causes a severe skin disorder in a family.

THAP1 gene changes do not affect DYT1 dystonia; finasteride may help reduce tics and OCD in Tourette syndrome.

Two new enzymes, PAD-R11 and PAD-R4, were cloned and showed activity, with PAD-R11 resembling epidermal enzymes.

Male cells need DHT to respond to testosterone, while female cells do not.

Low oxygen levels affect the behavior of certain proteins in human skin cells.

The compound 4c effectively inhibits the enzyme linked to hair loss.

A specific gene mutation causes long hair in Angora rabbits.

LHX2 is crucial for development, tissue repair, and preventing diseases.

Prostaglandin D2 increases testosterone levels in skin cells through reactive oxygen species, not enzymes, which could lead to new hair loss treatments.

A rabbit gene important for hair development was identified and detailed.

The treatment was not recommended due to limited effectiveness and significant side effects.

TPA strongly increases ODC activity in certain skin cells, potentially aiding tumor growth.

Double-stranded RNA activates a pathway that causes a skin protein to be expressed in the wrong place.

Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.

The TT genotype of a specific SNP in sheep is linked to better wool quality.

ODC transgenic mice can model human hair loss with skin lesions.

A specific gene region can control targeted and responsive gene expression in mice, useful for skin disorder treatments.