6 citations
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October 2022 in “Frontiers in Physiology” Calcium channels are vital for normal skin function and their dysfunction can lead to skin issues.
134 citations
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June 2012 in “International Journal of Oral and Maxillofacial Surgery” Facial feminization surgery is effective in helping transgender women appear more feminine and has high patient satisfaction.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
5 citations
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January 2001 in “Advances in protein chemistry” 5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.
16 citations
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April 2017 in “Journal of Cosmetic Dermatology” Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
186 citations
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December 2011 in “Molecules” Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.
January 2025 in “Open Life Sciences” Overexpression of the HE4 gene in mice causes eye inflammation and cloudiness.
1 citations
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March 2023 in “Science Translational Medicine” Blocking a certain signal in the gp130 receptor can improve tissue healing and lessen osteoarthritis symptoms.
August 2019 in “The Journal of Urology” Treatment with 5α-reductase inhibitors is linked to a delay in prostate cancer diagnosis and may affect survival rates.
1 citations
,
October 2008 in “Expert Review of Dermatology” Frontal Fibrosing Alopecia is a slowly progressing hair loss condition, likely underdiagnosed, with ineffective treatments, needing more research to understand it fully.
30 citations
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December 2017 in “Journal of The American Academy of Dermatology” New criteria for diagnosing frontal fibrosing alopecia include specific scalp and eyebrow hair loss as major factors and other hair loss areas and hair analysis as minor factors.
48 citations
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January 2011 in “Neuropharmacology” Isolation stress in rats reduces brain enzyme levels, affecting dopamine function.
4 citations
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December 2013 in “British Journal of Dermatology” ESR2 gene linked to female-pattern hair loss.
July 2025 in “Saudi Journal of Medicine and Public Health” 5α-reductase inhibitors effectively treat enlarged prostate and hair loss but require careful use due to possible side effects.
1 citations
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July 2018 in “Elsevier eBooks” FAPD and possibly CCCA may be AGA subtypes, and treatments combining antiandrogens, hair growth agents, hair transplants, and anti-inflammatories could be effective.
October 2020 in “International Journal of Research in Dermatology” The review suggests more research is needed to understand Frontal fibrosing alopecia, a condition causing hairline recession in postmenopausal women.
79 citations
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June 1993 in “Molecular and Cellular Biology” The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.
April 2017 in “Austin Journal of Cancer and Clinical Research” 5α-reductase inhibitors like Finasteride and Dutasteride may help manage prostate cancer by blocking testosterone conversion.
2 citations
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July 2022 in “Frontiers in Medicine” The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.
55 citations
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August 2013 in “PloS one” Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.
147 citations
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June 2011 in “New England journal of medicine/The New England journal of medicine” 5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.
January 2011 in “Xibei nongye xuebao” The K14 promoter is more active in skin cells than the K5 promoter.
1 citations
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December 2021 in “Development & Reproduction” Lack of FPR2 slows hair growth by affecting hair cell activity.
August 2019 in “Journal of the American Academy of Dermatology” Frontal fibrosing alopecia may be caused by an autoimmune reaction and hormonal imbalance.
1 citations
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January 2013 in “MedChemComm” PF-05314882 selectively activates androgen receptors without much effect on prostate and may help in prostate cancer treatment and hair loss prevention.
19 citations
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August 2022 in “Plant Signaling & Behavior” ROS and calcium oscillations are essential for root hair growth in plants.
January 2008 in “Journal of The American Academy of Dermatology” ROS may affect hair loss related to hormones.
December 2016 in “Anales del sistema sanitario de Navarra” Frontal fibrosing alopecia is increasing, especially in postmenopausal women, and treatment with finasteride can improve it.
September 2025 in “Digital Commons - RU (Rockefeller University)” FOXC1 is essential for keeping hair follicle stem cells inactive and maintaining their environment for healthy hair growth.
8 citations
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October 2019 in “International Journal of Dermatology” The study concluded that combination therapy with topical corticosteroids and hydroxychloroquine or finasteride is effective in treating Frontal fibrosing alopecia in Asians.