99 citations
,
April 2005 in “Journal of Dermatological Treatment” Finasteride effectively treats hidradenitis suppurativa for most patients.
81 citations
,
June 2014 in “American Journal of Men's Health” Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
78 citations
,
January 2000 in “Gynecological Endocrinology” Norgestimate is the most effective birth control progestin for reducing an enzyme linked to acne and excessive hair growth in women.
65 citations
,
March 1999 in “Urology” Finasteride didn't significantly improve ICPPS symptoms, more research needed.
62 citations
,
March 2013 in “JAMA Dermatology” Finasteride reduces Hidradenitis Suppurativa flare-ups in children and teens, but long-term safety is unknown.
59 citations
,
January 2011 in “Retina-the Journal of Retinal and Vitreous Diseases” Finasteride may help treat chronic CSC, improving vision.
49 citations
,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.
49 citations
,
December 1997 in “Urology” Tamoxifen effectively treats gynecomastia without causing impotence.
39 citations
,
November 2015 in “Nanomedicine” Improved Finasteride delivery for hair loss treatment.
38 citations
,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Finasteride effectively improves hair growth and slows hair loss in men with male pattern baldness.
38 citations
,
January 1997 in “Gynecological Endocrinology” Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.
36 citations
,
November 2020 in “Journal of The European Academy of Dermatology and Venereology” 5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.
36 citations
,
February 2011 in “Fertility and Sterility” Finasteride use may cause sperm damage and infertility, stopping it can improve sperm health.
34 citations
,
July 2011 in “Journal of Dermatological Treatment” Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.
34 citations
,
January 2004 in “Revista do Hospital das Clínicas” Finasteride may worsen infertility in men with existing issues, but stopping it can improve sperm health.
30 citations
,
January 1997 in “Journal of Dermatological Treatment” Topical finasteride helps regrow hair and reduce balding without side effects.
29 citations
,
January 1996 in “Journal of Pharmaceutical Sciences” Finasteride poorly inhibits type 1 5AR, affecting its effectiveness.
28 citations
,
May 2018 in “Scientific reports” Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
24 citations
,
December 2013 in “Sexual medicine reviews” Finasteride can cause sexual problems and depression in young men.
23 citations
,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
20 citations
,
August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
19 citations
,
July 2017 in “Pediatric Dermatology” Finasteride improves hidradenitis suppurativa in children with no adverse effects.
17 citations
,
December 2018 in “The World Journal of Men s Health” Long-term use of dutasteride can cause permanent erectile dysfunction in rats.
17 citations
,
September 2013 in “The International Journal of Neuropsychopharmacology”
14 citations
,
January 2020 in “Biomaterials Science” Created microspheres show potential for safe and effective use in prostate artery embolization.
14 citations
,
January 2020 in “International Journal of Biological Sciences” Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
14 citations
,
October 2016 in “Psychoneuroendocrinology” Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.
13 citations
,
March 2019 in “Journal of Dermatological Treatment” Finasteride can treat hair loss, but may have side effects; evaluate and inform patients of risks.
13 citations
,
November 2012 in “PubMed” 5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.
13 citations
,
January 2005 in “Chemical and Pharmaceutical Bulletin” Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.