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The P133R mutation in AKR1D1 enzyme causes harmful bile acid buildup, explaining related health issues.

Activating androgen receptors in muscle can increase muscle mass and reduce fat.

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

OXI1 kinase is essential for plant defense and root hair growth in Arabidopsis.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

Transglutaminases work through a ping-pong mechanism, and human plasma and platelet transglutaminases have similar catalytic subunits.

Scientists discovered two versions of a new human hair keratin gene.

Reconstructed skin models are useful for studying how skin processes certain chemicals.

Nanozymes greatly improve biocatalysis by being stable, efficient, and versatile.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

The method reliably profiles eicosanoids and shows epitestosterone reduces their levels, similar to common anti-inflammatory drugs.

5α-reductases increase epitestosterone's effect on androgen receptors.

Ischemia-modified albumin is not effective for diagnosing stable angina compared to exercise stress tests.

5α-reductase inhibitors may reduce male fertility and could be used for male contraception.

The method effectively measures drug impact on DHT levels in prostate treatments.

New compounds show promise as nonsteroidal treatments for hair loss.

Dutasteride may reduce insulin sensitivity and increase body fat.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

EISA uses enzymes to create precise nanostructures in cells, offering new ways to design adaptive materials and therapies.

Isoproterenol may help treat hair loss by activating hair follicle stem cells.

Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.

A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

IsoPSA test works accurately even if patients take certain prostate medications.

Hair plucking quickly increases antizyme, reducing a specific enzyme activity in rats.

A new method accurately measures nine specific hormones in human blood.

Chromosomal differences affect how muscle cells respond to testosterone.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

Ischemia-modified albumin can help diagnose ischemic conditions early, but better detection methods are needed.