56 citations
,
February 2012 in “Developmental biology” Sostdc1 controls the size and number of hair and mammary gland structures.
50 citations
,
May 2021 in “Frontiers in immunology” Certain immune cells contribute to skin autoimmune diseases, and some treatments can reverse hair loss in these conditions.
44 citations
,
February 2023 in “Cell” Fingerprints form uniquely before birth due to specific genetic pathways and local signals.
19 citations
,
October 2024 in “Molecular Pharmaceutics” Microneedles improve delivery of plant-based compounds through the skin, aiding treatments for hair loss, cancer, and wounds.
15 citations
,
July 2024 in “Current Issues in Molecular Biology” Understanding molecular processes in skin development is key to creating targeted treatments for skin disorders.
12 citations
,
November 2012 in “BioMolecular Concepts” PPAR β/δ is important for skin health and disease treatment, but more research is needed.
2 citations
,
September 2025 in “Future Journal of Pharmaceutical Sciences” Lupeol shows promise for hair growth but needs better absorption and safety testing.
June 2023 in “Frontiers in Bioengineering and Biotechnology” The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.
January 2023 in “Karger Kompass. Dermatologie” Scientists are still unsure what triggers the immune system to attack hair follicles in Alopecia areata.
124 citations
,
December 2016 in “Pharmaceuticals” TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.
3 citations
,
January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin cells from people with Epidermolysis Bullosa Simplex have abnormally placed and less active mitochondria.
May 2025 in “Scientific Reports” Oxyresveratrol promotes hair growth and may help treat hair loss.
24 citations
,
May 2012 in “International Journal of Dermatology” The document concludes that eyelash trichomegaly, which is the abnormal growth of eyelashes, can be present from birth, caused by diseases, or result from certain medications.
87 citations
,
September 2012 in “Journal of Cell Science” Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
49 citations
,
November 2021 in “Annual review of pathology” Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.
21 citations
,
April 2025 in “MedComm” Alopecia areata causes unpredictable hair loss, and more research is needed to fully understand and treat it effectively.
48 citations
,
December 2022 in “Biomolecules” 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
Advances in RNA research and skin models offer hope for better skin healing without scarring.
February 2026 in “Cosmetics” Perifollicular elastolysis is poorly understood, with limited treatment options and inconsistent results.
91 citations
,
January 2009 in “International Journal of Trichology” Different hair evaluation methods have their own pros and cons, and using multiple methods together is best for accurate hair loss diagnosis and tracking.
37 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” Facial hair restoration is generally successful and satisfying for patients when done with quality techniques and realistic expectations.
15 citations
,
November 2008 in “Facial Plastic Surgery” Hair restoration can sometimes result in unnatural-looking hair, wide scars, and poorly designed hairlines, but these issues can be corrected with careful planning, various techniques, and possibly medical therapy.
February 2026 in “Frontiers in Medicine” FUE hair transplants are generally safe but require careful planning to avoid rare complications.
Polarized microscopy helps identify hair irregularities in genetic disorders.
Avicennia marina extract and avicequinone C can potentially promote hair growth and treat hair loss by interfering with hair loss mechanisms and boosting growth factors.
1 citations
,
May 2016 in “Current Opinion in Pediatrics” Children's hair loss can be caused by various factors and should be treated with appropriate, age-specific methods and psychological support.
86 citations
,
August 2014 in “Journal of The American Academy of Dermatology” To diagnose hair loss, use a systematic approach including history, exams, and tests.
Afro-textured hair is more fragile and prone to certain scalp conditions, requiring careful treatment and more research for effective management.
239 citations
,
July 2002 in “Clinical and Experimental Dermatology” Low iron and L-lysine levels can cause hair loss in women, and increasing these nutrients can reduce hair shedding.
8 citations
,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.