research Targeting of Smoothened for therapeutic gain
Targeting the Smoothened receptor shows promise for treating certain cancers.
Search
for
Sort by
Research
870-900 / 1000+ resultsresearch Anabolic potential of bone mineral in human periosteal fibroblasts using steroid markers of healing
Bone mineral and minocycline boost bone cell growth, aiding healing.
research [Retracted] Fibroblasts in Scar Formation: Biology and Clinical Translation
Fibroblasts are crucial in scar formation and wound healing, with potential therapies aiming for scarless healing.
research Effect of ethnicity and treatments on in situ tensile response and morphological changes of human hair characterized by atomic force microscopy
Different ethnicities and treatments affect human hair strength and structure.
research Immunohistochemical analysis of tissue remodelling during the anagen—catagen transition of the human hair follicle
The inner root sheath is vital for hair follicle stability during growth changes.
research Molecular modeling of hair keratin/peptide complex: Using MM‐PBSA calculations to describe experimental binding results
Electrostatic interactions mainly stabilize the binding of peptides to hair keratin.
research Anti-androgenic therapy with finasteride improves cardiac function, attenuates remodeling and reverts pathologic gene-expression after myocardial infarction in mice
Finasteride improves heart function and repairs damage after heart attack in mice.
research Epithelial cell migration on laminins
Collagen XVII and CD151 affect cell movement, with CD151 inhibiting migration when bound to integrins.
research Stabilization of epithelial β-catenin compromises mammary cell fate acquisition and branching morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research The muscarinic acetylcholine receptor in dermal papilla cells regulates hair growth
Muscarinic acetylcholine receptors help regulate and promote hair growth.
research Serine-rich ultra high sulfur protein gene expression in murine hair and skin during the hair cycle
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research EGFR : stopping stathmin to start the cycle
EGFR helps hair follicles transition properly by controlling Stathmin levels.
research Activation of the OVOL1-OVOL2 Axis in the Hair Bulb and in Pilomatricoma
The genes OVOL1 and OVOL2 are important for hair growth and may be involved in a type of skin tumor.
research Mechanism of astragaloside A against lung adenocarcinoma based on network pharmacology combined with molecular dynamics simulation technique
Astragaloside A may help fight lung cancer by targeting specific proteins.
research Androgenetic alopecia: new insights into the pathogenesis and mechanism of hair loss
New model shows muscle affects hair loss differently in men and women.
research Cardiac morphologic alterations in acute minoxidil cardiotoxicity in miniature swine
research 251 Morphogenetic events in hair follicle heterotypic spheroids
The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.
research Proliferation, but Not Apoptosis, Is Associated with Distinct β-Catenin Expression Patterns in Non-Small-Cell Lung Carcinomas
Distinct β-catenin patterns are linked to cell growth, not cell death, in lung cancer.
research Conditioned medium from human adipose-derived mesenchymal stromal cells can modulate cell migration and morphology of keratinocytes in vitro
MSC-CM can boost skin cell growth and movement, aiding skin repair.
research Minoxidil cyclodextrin complexes and their inclusion in transfersomes for the enhancement of therapeutic effect on androgenic alopecia
The new minoxidil formulation could better promote hair growth for treating androgenic alopecia.
research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts
Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.
research Homo- and heteropolymer self-assembly of recombinant trichocytic keratins
Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
research AMP-activated Protein Kinase 활성체인 Metformin의 모발 성장에 미치는 영향
Metformin promotes hair growth by affecting cell growth and protein signaling related to hair growth.
research Functional analysis of thymosin beta-4 using over-expressing transgenic mice
Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
research Macrophages maintain mammary stem cell activity and mammary homeostasis via TNF-α-PI3K-Cdk1/Cyclin B1 axis
Macrophages help maintain mammary stem cells and tissue balance through specific signaling pathways.
research A comprehensive investigation into the molecular mechanism responsible for selective androgen receptor (SARM) tissue-selectivity
SARMs work differently in tissues due to unique interactions and structures.
research Allosteric interactions prime androgen receptor dimerization and activation
Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.
research Trichohyalin, an intermediate filament-associated protein of the hair follicle.
Trichohyalin is a protein in hair follicles that helps form hair filaments.
research ‘Malignant melanoma microecosystem’: Immunohistopathological insights into the stromal cell phenotype
Stromal cells in melanoma promote tumor growth and spread.