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GlossaryAdenosine Monophosphate

molecule involved in cellular energy transfer and metabolism

Adenosine Monophosphate (AMP) is a molecule that plays a crucial role in cellular energy transfer. It is one of the components of RNA and is involved in various biochemical processes, including the regulation of energy metabolism and signal transduction pathways. In simpler terms, AMP helps cells manage and use energy efficiently.

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Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research Leptin and the skin: a new frontier

108 citations , July 2009 in “Experimental Dermatology”

Leptin may improve skin regeneration and hair growth, and help reverse skin aging.

research Topical metformin as a novel therapy for alopecia areata due to its immunologic effects

August 2023 in “Medical Hypotheses”

Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.

research A Review of Metabolic Dysregulation in Lymphocytic Cicatricial Alopecia: Exploring the Connections and Therapeutic Implications

1 citations , March 2025 in “Journal of Investigative Dermatology”

Metabolic issues may trigger lymphocytic cicatricial alopecia, and treatments targeting these issues could help.

research Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport

December 2023 in “Journal of ethnopharmacology”

Tribuloside can increase skin pigmentation by enhancing melanin production and distribution.

research Enzymes

March 2008 in “British Journal of Pharmacology”

Enzymes play crucial roles in metabolism, health, and disease management.

research Nonanal Stimulates Growth Factors via Cyclic Adenosine Monophosphate (cAMP) Signaling in Human Hair Follicle Dermal Papilla Cells

8 citations , October 2020 in “International Journal of Molecular Sciences”

Nonanal from fruits and vegetables promotes hair growth by increasing growth factors.

research Carvone Decreases Melanin Content by Inhibiting Melanoma Cell Proliferation via the Cyclic Adenosine Monophosphate (cAMP) Pathway

12 citations , November 2020 in “Molecules”

Carvone helps treat skin issues by reducing melanin and stopping harmful cell growth.

research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes

6 citations , November 2022 in “Antioxidants”

OR2AT4 helps reduce aging and cell damage in human skin cells.

research Dissecting the Impact of α-MSH-MC1R-cAMP Signaling on UVA-Induced Stress in Fibroblasts - Implications for Regulation of Cutaneous Photoaging

January 2026 in “Aging and Disease”

The α-MSH-MC1R-cAMP pathway does not protect skin cells from UVA damage.

research Proteome Analysis of Alpine Merino Sheep Skin Reveals New Insights into the Mechanisms Involved in Regulating Wool Fiber Diameter

October 2023 in “International journal of molecular sciences”

Key proteins and pathways regulate wool fiber diameter in Alpine Merino sheep.

Salicylate Induces Epithelial Actin Reorganization via Activation of the AMP-Activated Protein Kinase and Promotes Wound Healing and Contraction in Mice

research Salicylate induces epithelial actin reorganization via activation of the AMP-activated protein kinase and promotes wound healing and contraction in mice

8 citations , July 2024 in “Scientific Reports”

Salicylate helps wounds heal without scarring in mice.

research Historical and Current Adenosine Receptor Agonists in Preclinical and Clinical Development

142 citations , March 2019 in “Frontiers in Cellular Neuroscience”

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

ATP-Competitive mTOR Kinase Inhibitors Delay Plant Growth by Triggering Early Differentiation of Meristematic Cells Without Developmental Patterning Change

research ATP-competitive mTOR kinase inhibitors delay plant growth by triggering early differentiation of meristematic cells but no developmental patterning change

161 citations , August 2013 in “Journal of experimental botany”

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

research Advances in nucleoside monophosphate prodrugs as anti-HCV agents

52 citations , October 2010 in “Antiviral Therapy”

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap

3 citations , October 2010 in “Epilepsy Currents”

Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.

research Neurosteroids on the Epilepsy Chessboard—Keeping Seizures in Check

October 2010 in “Epilepsy Currents”

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

research Are STK11 polymorphisms a predictor of the response to metformin in polycystic ovarian syndrome?

June 2022 in “Biomedical reports”

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

research Applications of Marine Organism-Derived Polydeoxyribonucleotide: Its Potential in Biomedical Engineering

14 citations , May 2021 in “Marine Drugs”

PDRN, derived from salmon sperm, shows promise in healing wounds, reducing inflammation, and regenerating tissues, but more research is needed to understand its mechanisms and improve its use.

research Steroidogenic factor-1 lineage origin of skin lesions in Carney complex syndrome

January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)”

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

research The Metabolism and Control Mechanism of Human Hair Follicles

22 citations , April 2015 in “Current problems in dermatology”

Human hair follicles have a unique metabolism that changes between growth stages and may contribute to baldness.

research The Changing Landscape of Alopecia Areata: The Therapeutic Paradigm

77 citations , June 2017 in “Advances in Therapy”

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

research A novel therapeutic paradigm for patients with extensive alopecia areata

30 citations , May 2016 in “Expert Opinion on Biological Therapy”

New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.

research New drugs under investigation for the treatment of alopecias

26 citations , January 2019 in “Expert Opinion on Investigational Drugs”

New treatments for hair loss show promise, but more research is needed to confirm their safety and effectiveness.

research Reversing Gray Hair: Inspiring the Development of New Therapies Through Research on Hair Pigmentation and Repigmentation Progress

2 citations , January 2023 in “International journal of biological sciences”

Gray hair can potentially be reversed, leading to new treatments.

research Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome

3 citations , June 2025 in “Drug Design Development and Therapy”

Targeting glycolysis may help treat PCOS by improving insulin sensitivity and ovarian function.

research 873 The effect of Cilostazol on hair growth: A novel therapeutic option for the treatment of hair loss

1 citations , April 2017 in “Journal of Investigative Dermatology”

Cilostazol may help hair grow and could be a new treatment for hair loss.

Hair Thickness Growth Effect of Adenosine Complex in Male and Female Patterned Hair Loss via Inhibition of Androgen Receptor Signaling

research Hair Thickness Growth Effect of Adenosine Complex in Male-/Female-Patterned Hair Loss via Inhibition of Androgen Receptor Signaling

June 2024 in “International journal of molecular sciences”

Adenosine complex helps increase hair thickness and density in hair loss.

research Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis

8 citations , July 2024 in “Journal of Advanced Research”

CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.

research Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases

1 citations , May 2024 in “International Journal of Molecular Sciences”

Adenosine receptors could be promising targets for treating inflammatory skin diseases like psoriasis.