106 citations
,
August 2021 in “Pharmaceuticals” Extracellular vesicles help heal skin wounds and could be used for better treatments.
105 citations
,
October 2017 in “Stem cells” Wnt signaling is crucial for skin development and hair growth.
98 citations
,
May 2020 in “Journal of Functional Morphology and Kinesiology” Exercise, especially vigorous aerobic and resistance training, can improve hormone levels in women with PCOS.
97 citations
,
May 2019 in “Frontiers in Cell and Developmental Biology” Abnormal ECM and immune cell interactions can cause skin diseases.
89 citations
,
August 2013 in “PloS one” Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
81 citations
,
February 2016 in “Veterinary pathology” Progeroid mouse models show signs of early aging similar to humans, helping us understand aging better.
74 citations
,
October 2023 in “Nature Reviews Molecular Cell Biology” 74 citations
,
August 2023 in “Frontiers in Immunology” Fibroblasts are key to wound healing by managing immune cells and forming scar tissue.
74 citations
,
January 2014 in “Journal of Investigative Dermatology” High kallistatin levels in diabetics worsen wound healing by blocking important cell signals.
72 citations
,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
70 citations
,
August 2006 in “Cancer Research” AP-1 controls tumor cell type by affecting key signaling pathways.
61 citations
,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
58 citations
,
March 2011 in “Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere/Pflügers Archiv” Hormones and signaling pathways control sebaceous gland function and could help treat acne.
56 citations
,
March 2015 in “Journal of Investigative Dermatology” Healthy mitochondria in skin cells are essential for proper hair growth and skin cell interaction in mice.
55 citations
,
March 2014 in “EMBO Reports” Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
52 citations
,
January 2023 in “Annual Review of Immunology” Immune-epithelial interactions are crucial for tissue repair, but unchecked can cause diseases.
48 citations
,
December 2022 in “Biomolecules” 3D bioprinting shows promise for creating advanced skin for healing wounds and reducing animal testing.
46 citations
,
September 2023 in “Cell Reports” Sebaceous glands can regenerate after injury using stem cells from hair follicles.
46 citations
,
June 2015 in “American Journal Of Pathology” Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
45 citations
,
May 2022 in “Biomedicines” Analyzing follicular fluid can help predict and improve outcomes for women with PCOS undergoing fertility treatments.
45 citations
,
August 2018 in “Stem Cells International” Stem cells, especially from fat tissue and Wharton's jelly, can potentially regenerate hair follicles and treat hair loss, but more research is needed to perfect the treatment.
44 citations
,
July 2020 in “Stem Cell Research & Therapy” Epidermal stem cells show promise for skin repair and regeneration.
42 citations
,
July 2021 in “Frontiers in Cell and Developmental Biology” Oral mucosa heals with minimal scarring, offering insights for scarless wound healing.
42 citations
,
September 2012 in “PLoS ONE” Bezafibrate treatment improved skin and spleen health in aging mice but didn't extend lifespan.
38 citations
,
February 2021 in “Journal of Investigative Dermatology” Aging slows wound healing due to weaker cells and immune response.
38 citations
,
January 2017 in “PPAR Research” PPAR-γ helps control skin oil glands and inflammation, and its disruption can cause hair loss diseases.
37 citations
,
May 2021 in “Frontiers in Cell and Developmental Biology” Ng2+ perivascular cells in mouse skin come from specific fibroblast types and help in tissue repair.
36 citations
,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Canine hair follicles have stem cells similar to human hair follicles, useful for studying hair disorders.
35 citations
,
January 2024 in “BioMolecular Concepts” Lifestyle changes, exercise, and antioxidants can help manage polycystic ovary syndrome.
33 citations
,
February 2024 in “International Journal of Molecular Sciences” Understanding fibroblast issues in diabetic foot ulcers is key to creating better treatments.