November 2023 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Upadacitinib helped regrow hair in a severe alopecia areata patient but stopping treatment caused hair loss to return.
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” A certain gene variation is linked to a higher risk of polycystic ovarian syndrome in South Indian women.
September 2016 in “Springer eBooks” Fat-derived stem cells may help treat skin aging and hair loss.
Arabidopsis Formin 2 stabilizes actin filaments to aid cell-to-cell trafficking.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.
Amino acid storage proteins are essential for maintaining stem cells in female fruit flies.
January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences” Patients with acne vulgaris have lower serum irisin levels.
19 citations
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September 2019 in “British Journal of Dermatology” FOL-005 peptide can reduce human hair growth by lowering FGF7 levels.
Correcting EDA fibronectin organization and YAP translocation can improve wound healing in fibrotic conditions.
August 1994 in “Molecular Endocrinology” Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.
282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry” Apple polyphenol, especially oligomeric procyanidins, can reduce fat absorption and lower blood fat levels.
32 citations
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August 1996 in “Journal of Investigative Dermatology” April 2016 in “Journal of Investigative Dermatology” CD73 may regulate hair growth and could be targeted for hair growth treatments.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” JAK inhibitors help hair growth by boosting beta-catenin activity in hair root cells.
September 2025 in “Frontiers in Medicine” Angiopoietin-1 helps hair cells survive and grow, making it a potential treatment for hair loss.
January 2014 in “Journal of Investigative Dermatology” Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
25 citations
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May 2020 in “Stem Cells Translational Medicine” ADSC-CE treatment safely increases hair density and thickness in androgenetic alopecia patients.
30 citations
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October 2014 in “Experimental Dermatology” Leptin from skin fat can slow hair growth during certain phases.
23 citations
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March 1994 in “Fertility and sterility” Most patients improved with oral contraceptives, but some needed additional treatment.
7 citations
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March 2011 in “Hormone and Metabolic Research” Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
Lower serum irisin levels are linked to androgenetic alopecia but not to insulin resistance.
July 2024 in “Journal of Investigative Dermatology” Reactive lipids from aging cells change the extracellular matrix, affecting cell function and inflammation.
21 citations
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September 2019 in “International Journal of Nanomedicine” RADA16-I can effectively deliver and release mangiferin, improving its solubility and bioavailability.
January 2025 in “Clinical and Translational Medicine” A specific RNA can help hair growth in baldness by boosting stem cell activity.
August 2023 in “MOJ women's health” Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
May 2023 in “Journal of Cosmetic Dermatology” Androgenetic alopecia is linked to higher cardiovascular and metabolic risks, possibly due to irisin resistance.
May 2026 in “Electronic Journal of General Medicine” Irisin and betatrophin levels change differently in PCOS, which may help assess metabolic risks.
1 citations
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June 2000 in “PubMed” Osteopontin may help hair follicle growth during the catagen phase.
January 2026 in “Scientific Reports” Sesamin may help treat hair loss by affecting specific cell pathways.
16 citations
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April 1998 in “Journal of Investigative Dermatology” ACTH promotes hair growth in mink, but α-MSH does not.