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Combining flutamide and finasteride can reduce prostate weight and tumor growth, potentially benefiting treatments needing optimal DHT inhibition.

AD198 is more effective than doxorubicin in stopping certain dog cancer cells.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Androgen receptor inactivation delays skin cancer onset and reduces incidence in mice, with gender differences in susceptibility.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Upadacitinib helped regrow hair in a severe alopecia areata patient but stopping treatment caused hair loss to return.

Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.

Adverse events in lung cancer treatments increase fear, anxiety, and depression, with newer therapies causing fewer side effects.

A new compound, 3a, effectively fights prostate cancer better than finasteride.

Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.

Dabrafenib was effective and well tolerated in treating thyroid cancer with a specific mutation.

Alfuzosin reduces short-term surgery need after catheter removal, but long-term benefits are unclear; combination therapy may help prevent urinary issues.

5-Alpha Reductase Inhibitors are effective for male hair loss and some skin conditions, but their effectiveness in women and safety concerns require careful use.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

A woman's adrenal tumor disappeared after treatment with cyproterone acetate.

Patients with advanced breast cancer prioritize quality of life, overall survival, and progression-free survival in treatment decisions.

Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.

GnRH-a or orchiectomy is more effective than anti-androgens for managing hormone levels in transgender women.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

Ritlecitinib shows promise for treating alopecia areata, especially with early and extended treatment.

Testosterone with dutasteride improves muscle strength and body composition in trans men.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Using temgikoluril with alopecia treatment reduces anxiety and improves satisfaction.

Future hormone therapy trials should match the diverse needs and priorities of the gender-diverse community.