research Effect of injectable calcium alginate-amelogenin hydrogel on macrophage polarization and promotion of jaw bone osteogenesis
The hydrogel helps bone growth and healing in jaw and facial defects.
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90-120 / 1000+ resultsresearch A molecular systems architecture of the mesenchymal stromal cell microenvironment
A systems biology approach helps improve mesenchymal stromal cell therapies by mapping interactions and identifying treatment targets.
research 965 The importance of CD206+ macrophages in squaric acid dibutylester-induced hair cycle activation
CD206+ macrophages are crucial for hair growth in alopecia areata treatment.
research ABCD1 Gene Mutations: Mechanisms and Management of Adrenomyeloneuropathy
ABCD1 gene mutations cause adrenomyeloneuropathy, leading to symptoms like limb weakness and spasticity, with management focusing on rehabilitation and spasticity treatment.
research Harnessing mesenchymal aggregation for engineered organ‐level regeneration: Recent progress and perspective
Scientists are using clumps of special stem cells to improve organ repair.
research Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands
Two new compounds were found to build bone and muscle without affecting reproductive organs and skin oil glands.
research A Transition State Analogue of 5′-Methylthioadenosine Phosphorylase Induces Apoptosis in Head and Neck Cancers
MT-DADMe-ImmA can selectively kill head and neck cancer cells without harming normal cells.
research Immunization and Bacterial Pathogens in the Oropharynx as Risk Factors for Alopecia Areata
Immunization and throat bacteria may increase the risk of a hair loss condition called alopecia areata.
research Early Encouraging Results of a Non-Arthroscopic Autologous Cartilage Micrografting Technology for Knee Osteoarthritis
AMT® shows promise as a safe and effective treatment for early-stage knee osteoarthritis.
research Selective androgen receptor modulators: a critical appraisal
SARMs show promise but need more evidence to prove they're better than traditional androgens.
research Coordinating the Sculptors: Ectodysplasin-A (EDA) Signaling Cross-Talk with Skeletogenic Pathways
EDA is vital for bone and cartilage formation and could help treat skeletal disorders.
research SB216763-loaded multifunctional copper-doped bioglass 3D printed scaffold promotes wound healing and functional skin regeneration
The 3D printed scaffold with SB216763 and copper helps heal wounds and regrow skin and hair.
research A comprehensive investigation into the molecular mechanism responsible for selective androgen receptor (SARM) tissue-selectivity
SARMs work differently in tissues due to unique interactions and structures.
research The Androgen Receptor and Its Use in Biological Assays: Looking Toward Effect-Based Testing and Its Applications
Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.
research Asymmetric adhesive SIS-based wound dressings for therapeutically targeting wound repair
The new wound dressing improves healing and tissue repair better than conventional dressings.
research Dissecting the microenvironment around biosynthetic scaffolds in murine skin wound healing
The Aligned membranes improved wound healing and hair growth with a better immune response in mice.
research Changes in the proteomic profile of adipose tissue-derived mesenchymal stem cells during passages
Adipose stem cells show common protein changes as they grow, especially involving S100A6.
research Male Androgenetic Alopecia — Endotext
Male androgenetic alopecia (MAA) is a common, hereditary hair loss condition in men, linked to heart disease, and can be treated with minoxidil, finasteride, or hair transplantation.
research 26SCS-Loaded SilMA/Col Composite Sponge with Well-Arranged Layers Promotes Angiogenesis-Based Diabetic Wound Repair by Mediating Macrophage Inflammatory Response
The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.
research Improving selective androgen receptor modulator discovery and preclinical evaluation
We need better ways to test and understand SARMs to make safer and more effective treatments.
research Converging physiological roles of the anthrax toxin receptors
CMG2 and TEM8 receptors have distinct roles in skin and growth disorders, affecting collagen breakdown and growth.
research Application of Scaffold-Based Drug Delivery in Oral Cancer Treatment: A Novel Approach
Scaffold-based drug delivery systems improve oral cancer treatment by targeting drugs directly to cancer cells, reducing side effects.
research Axolotl-derived decellularized skin ECM as a pro-regenerative scaffold for attenuating fibrotic wound healing
Axolotl-derived skin scaffolds may help heal wounds better by reducing scarring.
research Vitamin D3 and chemotherapy-induced alopecia
Vitamin D3 may prevent hair loss from chemotherapy, but side effects and cancer cell protection are concerns.
research Studies of the availability of soil phosphorus (P) and potassium (K) in organic farming systems, and of plant adaptations to low P- and K-availability
Organic farms need to supplement phosphorus and potassium to maintain soil health and crop yields.
research Caring for women with polycystic ovary syndrome
Treating PCOS is complex, involving medication like metformin and lifestyle changes, and requires attention to mental health due to high depression and anxiety rates.
research The Clinical Center’s Blood Glucose Management Service
The Blood Glucose Management Service improved patient safety and outcomes in managing blood sugar in hospitalized patients.
research Anti-inflammatory loading of cinnamaldehyde on artificial bone scaffolds against the process of bone regeneration
Cinnamaldehyde helps bone healing initially but may slow healing later unless combined with DHT treatment.
research Recombinant Human Annexin A5 Ameliorates Localized Scleroderma by Inhibiting the Activation of Fibroblasts and Macrophages
Recombinant Human Annexin A5 may help treat localized scleroderma by reducing skin thickening and inflammation.