October 2024 in “Journal of the Endocrine Society” Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.
49 citations
,
January 2009 in “The Journal of Clinical Endocrinology & Metabolism” DHEA treatment helps grow pubic hair and boosts mood in girls with adrenal issues.
CRH causes hair loss by reducing autophagy and increasing cell death in hair cells.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
2 citations
,
December 2001 in “Dermatologic Therapy” Steroids may not work well for alopecia areata because of high unoccupied receptors and low thioredoxin levels.
February 2025 in “Cureus” Early diagnosis and treatment of NCCAH can improve symptoms and fertility.
10 citations
,
July 2011 in “Archives of Pharmacal Research”
October 2022 in “European heart journal” Higher stress levels were found about two weeks before a heart attack.
Hair cortisol may help identify adrenal insufficiency in sickle cell disease patients.
Neurosteroids help control dopamine responses in the brain.
6 citations
,
August 1975 in “Journal of Endocrinology” Cortisol and corticosterone thin mouse skin and regress hair follicles, while testosterone promotes skin and hair development.
CRH causes hair loss by reducing cell survival in hair follicles.
10 citations
,
May 2014 in “The Journal of Steroid Biochemistry and Molecular Biology” Allopregnanolone increases KCC2 expression in baby male rats' brains, while finasteride doesn't affect it.
9 citations
,
January 2019 in “Postepy Dermatologii I Alergologii” The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
1 citations
,
November 2010 in “Anticancer Research” Finasteride and dutasteride both increase chromogranin A levels similarly.
9 citations
,
February 2019 in “Journal of Clinical Research in Pediatric Endocrinology” Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.
17 citations
,
November 2017 in “Experimental physiology” Breathing in newborn rats is affected differently by hormones based on their sex.
30 citations
,
March 1980 in “European Journal of Endocrinology” Adrenal androgens are important for puberty and are influenced by genetics.
August 2004 in “Veterinary Dermatology” Adult-onset hair loss in Chesapeake Bay retrievers may be linked to abnormal adrenal hormone production.
11 citations
,
May 2024 in “Reproductive Biology and Endocrinology” Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.
51 citations
,
June 1970 in “British journal of dermatology/British journal of dermatology, Supplement” Antiandrogens may help treat conditions like excessive hair growth, prostate tumors, male baldness, and acne by blocking male hormone effects.
January 2022 in “Current Enzyme Inhibition” New nonsteroidal molecules can potentially increase dihydrotestosterone in neurons by blocking certain enzymes, without affecting prostate and seminal vesicle weight.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” Topical glucocorticoids thin the skin and change collagen structure.
65 citations
,
May 2006 in “Journal of Investigative Dermatology” Dexamethasone may influence hair growth by altering estrogen receptor activity in hair cells.
May 2011 in “Journal of pediatric nursing” A patient with congenital adrenal hyperplasia improved after adjusting her medication to prevent Cushing's syndrome symptoms.
February 2023 in “Reactions Weekly”
November 2022 in “Journal of the Endocrine Society” Immunotherapy for cancer caused a patient to develop a condition affecting hormone production, requiring ongoing hormone replacement therapy.
12 citations
,
October 1952 in “Experimental biology and medicine” Vitamin B12 and aureomycin reduce the negative effects of high doses of cortisone in rats.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
402 citations
,
August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.