research <p>The regenerative potential of skin and the immune system</p>
The skin's immune system helps it regenerate and fight infections.
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870-900 / 1000+ resultsresearch Fullerene C60 with cytoprotective and cytotoxic potential: prospects as a novel treatment agent in Dermatology?
Fullerene C60 shows promise as a new treatment for various skin conditions.
research Type XVII collagen coordinates proliferation in the interfollicular epidermis
Type XVII collagen helps control skin cell growth and could be a target for anti-aging treatments.
research Integrating stem cell biology and organoid technology for skin regenerative therapies
Combining stem cells and organoids could improve skin regeneration treatments.
research Cellular senescence in tissue repair: every cloud has a silver lining
Cell aging can be both good and bad for tissue repair.
research Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities
Guava leaf extract may help treat hair loss and protect cells by blocking certain genes and fighting damaging molecules.
research OR2AT4, an Ectopic Olfactory Receptor, Suppresses Oxidative Stress-Induced Senescence in Human Keratinocytes
OR2AT4 helps reduce aging and cell damage in human skin cells.
research Adenine supplement delays senescence in cultured human follicle dermal papilla cells
Adenine helps delay aging in human hair follicle cells.
research 621 An apple stem cell-derived extract increases epithelial stem cells number in the hair follicle bulge
Apple stem cell extract may increase the number of stem cells in a part of the hair follicle.
research Platelet Immune Interactions, Lifespan, and Senescence
Platelets play a key role in the immune system and their lifespan and aging are important for developing new treatments.
research 1327 Effect of ginsenoside Rd on dermal epidermal junction in fibroblast
Ginsenoside Rd may help improve skin aging by increasing collagen in the skin.
research Relationship between androgenic alopecia and white matter hyperintensities in apparently healthy subjects
Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.
research Hair growth control by innate immunocytes: Perifollicular macrophages revisited
Immune cells around hair follicles help control hair growth and could be targets for treating hair disorders.
research Antioxidants and Mitochondrial Bioenergetics
Antioxidants may help improve mitochondrial health and could be used to treat diseases related to cell damage.
research Sirtuins pathways and redox homeostasis: a pilot study on young and old monozygotic twins
The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.
research Ocular manifestations of Hutchinson-Gilford-Progeria syndrome: A rare presentation
The report shows a young man with Hutchinson-Gilford Progeria Syndrome had typical and additional eye problems related to the disease.
research The Skin at Different Ages
Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.
research COVID-19 and Sex Differences
Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
research Anti-oxidant and Anti-inflammatory Effects of Sinapic Acid in UVB Irradiation-Damaged HaCaT Keratinocytes
Sinapic acid may protect skin cells from UV damage and reduce inflammation, making it a promising anti-aging cosmetic ingredient.
research 1349 Inducing fate changes at the hair follicle stem cell nice
The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
research Research Progress on the Immunomodulatory Effects by Dang Gui (Radix Angelica sinensis) and Its Active Chemical Components
Dang Gui may help treat immune-related diseases by boosting and regulating the immune system.
research 1372 Modulation of YBX1 phosphorylation determines epidermal stem cell function
Changing YBX1 protein activity affects skin stem cell function and aging.
research Chronic graft versus host disease and skin
cGVHD often severely affects the skin, causing rapid aging and other issues.
research The secret identities of TMPRSS2: Fertility factor, virus trafficker, inflammation moderator, prostate protector and tumor suppressor
TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.
research Regard the end: Harnessing physiology to provide better understanding of the mechanisms underpinning frailty
Understanding how different body systems interact can improve how we prevent or treat frailty in aging.
research Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome
Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.
research Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells
Baricitinib reduces inflammation and improves cell health in premature aging cells.
research Editors’ Picks
Hair shaft miniaturization leads to hair follicle stem cell loss, suggesting Piezo1 as a potential treatment target.
research Decision letter: Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration
Smad4 is crucial for muscle repair, especially in aging, by promoting cell growth over differentiation.
research The Rotterdam Study: 2018 update on objectives, design and main results
The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.