81 citations
,
September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
December 2016 in “Int J Genet” Male pattern baldness is partly caused by specific genes, but most genetic factors are still unknown.
January 2016 in “Texas ScholarWorks (Texas Digital Library)” DORN1 receptor affects eATP-induced stomatal changes but not eADP in Arabidopsis thaliana.
27 citations
,
July 2013 in “Journal of Dermatological Science” The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.
20 citations
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January 2017 in “Experimental Dermatology” Igf1r helps regulate hair growth cycles.
6 citations
,
December 2023 in “Journal of Molecular Cell Biology” Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
April 2024 in “The Journal of experimental medicine/The journal of experimental medicine” Treg cells help repair and regenerate tissues by interacting with local cells.
4 citations
,
July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
9 citations
,
January 1997 in “Horticultura: Revista de industria, distribución y socioeconomía hortícola: frutas, hortalizas, flores, plantas, árboles ornamentales y viveros” PRC2 is not essential for hair follicle stem cell maintenance or hair growth.
40 citations
,
June 2009 in “Journal of Cutaneous Pathology” AGA patients have fewer hairs and smaller follicles; T:V ratio above 4:1 may indicate AGA.
January 2024 in “Aesthetic Plastic Surgery” Botox can help prevent hair loss by blocking cell death in scalp cells.
November 2022 in “Journal of Investigative Dermatology” Cell-based therapy using specific immune cells may help treat alopecia areata by promoting hair regrowth.
June 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” In alopecia areata, certain immune cells increase and express a protein linked to immune activation.
10 citations
,
November 2010 in “Journal of Dermatology” Longer CAG repeats in gene linked to more severe hair loss in females.
103 citations
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February 1972 in “Proceedings of the National Academy of Sciences” A unique enzyme in guinea pig hair follicles helps form protein cross-links in hair.
37 citations
,
November 2007 in “Journal of Biological Chemistry” Ku80 is a key receptor for Thymosin β4, affecting cell migration and wound healing.
2 citations
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November 2021 in “Cell Biology International” miR-122 causes hair loss by killing hair cells.
December 2023 in “Benha Journal of Applied Sciences” AGEs and their receptors play a significant role in hair loss by causing inflammation and oxidative stress.
3 citations
,
October 2021 in “The Application of Clinical Genetics” Certain gene changes in osteopontin are linked to higher risk of atopic dermatitis and asthma.
January 2022 in “Social Science Research Network” The Ar/miR-221/IGF-1 pathway is involved in male pattern baldness, with miR-221 potentially being a new target for treatment.
14 citations
,
November 2022 in “Development” Controlling transposable elements is crucial for successful tissue regeneration.
January 2007 in “日本看護学会抄録集 成人看護1” Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.
190 citations
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October 2002 in “The FASEB journal” Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.
33 citations
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June 2007 in “Gene Expression Patterns” CTIP2 may help in skin development and maintenance.
April 2025 in “International Journal of General Medicine” The G allele of IFITM3 rs12252 is linked to more severe COVID-19.
6 citations
,
September 2019 in “Archives of Dermatological Research” Found 32 genes linked to male baldness, affecting hair growth and stress-related pathways.
November 2024 in “BMC Research Notes” SIRT3 and SIRT7 genes may play a role in hair loss.
December 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The KDM1 gene helps Venus flytraps close by managing potassium ions.
2 citations
,
January 1993 Trichohyalin is a versatile protein involved in hair and skin structure.
22 citations
,
April 2004 in “Journal of Neurochemistry” Acute stress increases Y1 receptor gene expression in certain brain areas, but repeated stress does not.