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The protein DDX6 helps keep skin cells renewing properly by controlling the production of certain other proteins and breaking down those that cause cells to mature too quickly.

Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.

Cyclic ADP-ribose helps regulate calcium and signals that promote hair growth in hair follicle cells.

YAP1 helps fat cell formation by influencing the Hippo pathway.

CRH causes hair loss by reducing cell survival in hair follicles.

Dab2 protein is crucial for hair follicle stem cell renewal and preventing early aging.

AE can have varied symptoms and genetic causes, but zinc therapy helps.

The KRTAP7-1 gene is very similar across different cattle and yak breeds and likely plays a role in hair strength and shape.

Vitamin D receptor and hairless protein are essential for hair growth.

The LEF-1 binding site enhances gene expression in hair follicles, with other proteins aiding specific regulation.

A new mutation in the TRPS1 gene was found in a Ukrainian girl with Trichorhinophalangeal syndrome type I.

NKIRAS2 can suppress certain skin tumors but its effect on cancer varies with context and expression level.

JAK inhibitors effectively treat severe atopic dermatitis and alopecia areata.

The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.

p120-catenin helps control skin inflammation by regulating cadherin levels.

A specific gene variant (rs4833095) is linked to a higher risk of alopecia areata in Koreans.

Par3–mInsc and Gαi3 work together to ensure proper cell division orientation in skin development.

Not having the gene PLAAT3 leads to fat loss, high insulin resistance, and abnormal fat levels in the blood due to a disruption in fat cell development and function.

A genetic variant in the KRT25 gene causes tightly curled hair.

The type 3 IP3 receptor is important for controlling hair loss and growth.

NIPP1 is important for healthy skin and could help treat skin inflammation.

The CD44-CD49d complex boosts T cell activation and survival in autoimmune disease.

Targeting NMMHC IIA may help treat blood-brain barrier damage.

Krt6a-Cre transgenic mice help study gene effects on hair follicle development and tumor suppression.

Targeting the AhR pathway may help treat alopecia areata.

Upadacitinib cleared scalp alopecia areata in three patients and also improved atopic dermatitis with minimal side effects.

Blocking α1-integrin makes adult fibroblasts more like foetal ones, improving their movement and aiding wound healing.

JAK inhibitors may help improve symptoms in adults with APECED.

MOF controls skin development by regulating genes for mitochondria and cilia.