research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors
Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
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research Immunocosmeceuticals: An emerging trend in repairing human hair damage
Immuno-cosmeceuticals from chicken egg yolk can effectively repair and improve damaged hair.
research The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of β-catenin in mice
Wnt signaling is vital for cell growth, development, and cancer research.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.
research Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
research Complications of Cushing's syndrome: state of the art
Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
research Evidence-Based and Potential Benefits of Metformin in the Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Prospect of Stem Cell Conditioned Medium in Regenerative Medicine
Stem cell-derived conditioned medium shows promise for treating various medical conditions but requires standardized production and further validation.
research Androgen Therapy in Women: An Endocrine Society Clinical Practice Guideline
The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.
research Severe cutaneous adverse reactions to drugs
Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.
research Polymeric nanoparticles‐based topical delivery systems for the treatment of dermatological diseases
Polymeric nanoparticles show promise for treating skin diseases.
research Eph Receptors and Ephrins: Therapeutic Opportunities
Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
research Pathobiology of chemotherapy-induced hair loss
Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
research Effects of Visible Light on the Skin†
Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.
research Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells
Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
research Pharmacokinetics, toxicity, and activity of intravenous dextran sulfate in human immunodeficiency virus infection
Dextran sulfate was found to be toxic and ineffective for treating HIV.
research Mechanical and biological properties of keratose biomaterials
Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.
research Protoporphyrin IX: the Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway
Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.
research Feather arrays are patterned by interacting signalling and cell density waves
Feather patterns in birds are shaped by signaling interactions and cell movements, with EDA/EDAR crucial for pattern formation.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Central Opioid Inhibition of Neuroendocrine Stress Responses in Pregnancy in the Rat Is Induced by the Neurosteroid Allopregnanolone
In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
research Dermatologic Changes Associated With Interleukin 2 Administration
IL-2 treatment causes skin eruptions and other reversible side effects, and may play a role in psoriasis.
research Zinc: An Essential Trace Element for Parenteral Nutrition
Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.
research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes
Nanozymes show promise for effective and safe cancer treatment.
research Convergent Genesis of an Adult Neural Crest-Like Dermal Stem Cell from Distinct Developmental Origins
Skin-derived precursors in hair follicles come from different origins but function similarly.
research Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth
Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
research In vivo immunological toxicity in mice of carbon nanotubes with impurities
Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.