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Modifying steroidal inhibitors shows promise for developing new cancer treatments.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.

5-aminolevulinic acid therapy reduces acne by decreasing fat production in skin cells.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

RIPK1 inhibitors might help prevent alopecia areata.

Carthamus oxyacantha may help treat BPH by inhibiting 5α-reductase.

Alpha-ketoglutarate protects rabbit skin cells from oxidative damage by activating a specific cell pathway.

Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

12-Methoxy carnosic acid from rosemary might be a good natural treatment for hair loss.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

A new method was developed to accurately measure enzyme activity related to prostate health.

Rice bran extract might help prevent hair loss.

Inhibiting ODC can prevent UV-induced skin cancer.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

New steroid compounds may help with hormonal therapy and have potential benefits for glucose disorders, but more research is needed.

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

15-lipoxygenase helps keep skin healthy by reducing inflammation.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride and dutasteride have little effect on Type 2 Diabetes risk.

Ocimum basilicum L. and red Oryza sativa L. may help with hair loss and prostate issues.

Blood metabolites significantly influence alopecia areata risk.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

Ginsenoside compound K shows promise for treating metabolic diseases like diabetes and obesity.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Low PON1 levels may indicate and predict the severity of hair loss.

A molecule called α-ketobutyrate was found to extend lifespan and improve aging-related symptoms in worms and mice by activating certain cellular pathways and may help develop anti-aging treatments for humans.