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Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides and Their Effect on 5α-Reductase Isoform 2, Androgen Receptor, and Androgen-Dependent Glands

research Synthesis of novel andostane-N-cyclohexyl-17-carboxamides, and their effect on the 5α-reductase isoform 2, the androgen receptor, and androgen-dependent glands

November 2021 in “Pharmaceutical Sciences”

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

research 5alpha-reductase inhibitors/finasteride.

4 citations , January 1996 in “PubMed”

research 5-Alpha Reductase Inhibitors on Hypersexuality During the Manic Phase of Bipolar and Psychotic Patients; New Insight to a Well-Known Medicines

February 2025 in “Iranian journal of pharmaceutical research”

Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

research Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

9 citations , April 2019 in “International Journal of Molecular Sciences”

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

research We-P13:320 The clinical significance of serum 7-ketocholesterol levels in patients with metabolic syndrome or acute myocardial infarction

January 2006 in “Atherosclerosis Supplements”

research RETRACTED: Genetic causality and metabolite pathway identifying the relationship of blood metabolites and psoriasis

3 citations , July 2024 in “Skin Research and Technology”

research JAK1 Signaling Is Involved in the Induction of Mechanical Alloknesis in Atopic Dermatitis

November 2025 in “Biomedicines”

JAK1 inhibitors can help reduce itchiness in atopic dermatitis.

Methylation of CpG Islands in Promoter of Type 2 5-Alpha Reductase and Implications of Finasteride Resistance for BPH Therapy

research 102 Methylation of CpG islands in promoter of type 2 5-α reductase and implications of finasteride resistance for BPH therapy

March 2016 in “European Urology Supplements”

Methylation in specific gene region causes finasteride resistance in some BPH patients.

research Macrophage Polarization: A Novel Target and Strategy for Pathological Scarring

4 citations , October 2024 in “Tissue Engineering and Regenerative Medicine”

Molecular Mechanism of Avicennia Marina in Inhibiting Hepatitis C Virus Based on Network Pharmacology and Molecular Docking

research Molecular Mechanism of Avicennia marina (Forssk.) Vierh. in Inhibiting Hepatitis C Virus Based on Network Pharmacology and Molecular Docking

1 citations , April 2025 in “Tropical Journal of Natural Product Research”

Avicennia marina shows potential to treat Hepatitis C by targeting key proteins.

research Agglomerative clustering-based drugs graded for the risk signals of drug-induced cognitive disorder: a study on the FAERS database

April 2026 in “Therapeutic Advances in Drug Safety”

Finasteride is high-risk for cognitive disorders, while Carbidopa/Levodopa, Topiramate, and Clonazepam are moderate-risk.

research Antagonistic Effect of Potassium Iodide in Baldness due to Thallium Acetate

1 citations , October 1935 in “Nature”

Potassium iodide prevents hair loss and reduces toxicity from thallium acetate.

research Effective detoxification of Abrus precatorius Linn. seeds by Shodhana

6 citations , January 2013 in “Journal of Ayurveda and integrative medicine”

The detoxification process made Abrus precatorius seeds safe and effective for use.

research Chitosan stimulates root hair callose deposition and inhibits root hair growth

July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

Chitosan slows root hair growth and causes a buildup of callose at low concentrations, but at high concentrations, it only inhibits growth without callose buildup.

research A mutation in the type II hair keratin KRT86 gene in a Han family with monilethrix

3 citations , January 2011 in “生物医学研究杂志：英文版”

A new mutation in the KRT86 gene causes monilethrix in a Han family.

Effect of Methanol Extract of Etlingera Alba (Blume) A. D. Poulsen Stems on Caspase-3 Gene Suppression as an Apoptosis Marker in T47D Breast Cancer Cell Line In Vitro

research Pengaruh Ekstrak Metanol Batang Etlingera alba (Blume) A. D. Poulsen Terhadap Penekanan Genicaspase-3 sebagai Penanda Apoptosis pada Lini Sel Kanker Payudara T47D Secara In Vitro

June 2025 in “Jurnal Mandala Pharmacon Indonesia”

Etlingera alba extract may help treat breast cancer with fewer side effects.

research Morphologic and molecular characterization of two novel Krt71 (Krt2-6g) mutations: Krt71 rco12 and Krt71 rco13

51 citations , December 2006 in “Mammalian Genome”

30% Supramolecular Salicylic Acid in the Treatment of Mild to Moderate Acne Vulgaris on the Face: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

research 30% Supramolecular Salicylic Acid in the Treatment of Mild to Moderate Acne Vulgaris on the Face: A Systematic Review and Meta-analysis of Randomised Controlled Trials

April 2020

30% supramolecular salicylic acid is safe and effective for treating mild to moderate facial acne.

research Treatment of black hairy tongue with triamcinolone acetonide

7 citations , September 1962 in “Oral Surgery Oral Medicine Oral Pathology”

Triamcinolone acetonide effectively treated black hairy tongue.

research Kaempferol Rhamnosides from Geranium sibiricum as Aldose Reductase Inhibitors and Their Content by HPLC Analysis

4 citations , June 2020 in “Processes”

Geranium sibiricum may help manage diabetic complications by inhibiting a key enzyme.

research Phenyl Propanoid 1’s-1′-Acetoxychavicol Acetate Protects Against Testosterone-Induced Alopecia by Inhibiting Nadph Oxidase

April 2025

ACA from Alpinia galanga may prevent testosterone-related hair loss.

Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells

research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome K_ATPChannel Mutations in Intact Cells

1 citations , August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics”

Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.

research Liquid Chromatography-Mass Spectrometry Based Isotopic Abundance Ratio Analysis of the Consciousness Energy Healing Treated L-Cysteine

March 2021 in “Juniper Online Journal Material Science”

Energy healing treatment improved L-cysteine's stability, solubility, bioavailability, and shelf-life.

research Profile of the progesterone derivative chlormadinone acetate — Pharmocodynamic properties and therapeutic applications

33 citations , January 2009 in “Contraception”

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.