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research Non-competitive androgen receptor inhibition in vitro and in vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
research Supplementary data: Treatment of androgenetic alopecia with sublingual minoxidil in transgender people receiving testosterone
research Supplementary data: Treatment of androgenetic alopecia with sublingual minoxidil in transgender people receiving testosterone
research Verstärkter Haarwuchs unter Langzeittokolyse mit Fenoterol** unter Berücksichtigung von Testosteron, Androstandiol, Cortisol und ACTH*
Fenoterol treatment causes increased hair growth due to higher metabolism in hair follicles, not hormones.
research Multistage Transdermal Nitric Oxide Delivery System for the Efficient Treatment of Androgenic Alopecia
The new nitric oxide delivery system may effectively treat hair loss by improving hair follicle health and reducing inflammation.
research 503 Use of low-dose spironolactone in female pattern hair loss in a specialty alopecia clinic
Low-dose spironolactone effectively treats female pattern hair loss with mild side effects.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors
Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
research METABOLIC, REPRODUCTIVE OUTCOMES AND SIDE EFFECTS AFTER THE ADMINISTRATION OF 100 MG DEHYDROEPIANDROSTERONE (DHEA) IN WOMEN WITH AN ADEQUATE OVARIAN RESERVE
Taking 100 mg of DHEA daily for 16 weeks did not change metabolic and reproductive health significantly but increased certain ovarian markers with minimal side effects.
research Growth factor concentrations in platelet‐rich plasma for androgenetic alopecia: An intra‐subject, randomized, blinded, placebo‐controlled, pilot study
PRP growth factor concentrations vary, no significant hair growth difference found.
research Efficacy of Off-Label Topical Treatments for the Management of Androgenetic Alopecia: A Review
Some off-label treatments increase hair density, but long-term safety unknown.
research Inhibition of 5α-reductase in the nucleus accumbens counters sensorimotor gating deficits induced by dopaminergic activation
Finasteride may help improve certain brain function issues linked to dopamine.
research Phosphodiesterase inhibitors used in androgenic alopecia as a possible risk factor for testicular tumor
research Development of Hyperalgesia in Patients Treated with Autologous Platelet Rich Plasma Due to Androgenetic Alopecia
research Cortexolone 17a-propionate: Preclinical profile of a new topical, skin selective, steroidal antiandrogen
Clofazimine may be effective for treating ashy dermatosis.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Natural Scalp Hair Regression in Preclinical Stages of Male Androgenetic Alopecia and Its Reversal by Finasteride
Finasteride reverses early hair loss and promotes growth.
research The comparison of treatment with clobetasol propionate 0.05% and topical pimecrolimus 1% treatment in the treatment of alopecia areata
Clobetasol and pimecrolimus are similarly effective for alopecia areata, but pimecrolimus has fewer side effects and is preferred for long-term use.
research Alopecia Areata and Dexamethasone Mini-Pulse Therapy, A Prospective Cohort: Real World Evidence and Factors Related to Successful Response
Dexamethasone mini-pulse therapy is effective for alopecia areata but less effective for those with early onset or hypothyroidism.
research Effects of two estroprogestins containing ethynilestradiol 30mug and drospirenone 3 mg and ethynilestradiol 30mug and chlormadinone 2 mg on skin and hormonal hyperandrogenic manifestations
Both birth control pills improved hormone levels and skin conditions in women with hyperandrogenism, but the one with drospirenone was more effective.
research Finasteride niet werkzaam bij oudere vrouwen met androgene alopecia
Finasteride is not effective for older women with hair loss.
research Prescribing Habits for Androgenic Alopecia among Dermatologists in Spain in 2019–2020: A Cross-Sectional Study
In Spain, dermatologists most commonly prescribe topical minoxidil and oral finasteride for male hair loss, and topical minoxidil and oral contraceptives for female hair loss. The use of oral dutasteride and oral minoxidil has significantly increased over the past three years.
research Safety, tolerability, and pharmacokinetics of CG2001 in Chinese adult male subjects with androgenetic alopecia: a randomized, double-blind, placebo-controlled, single- and multi-doses, phase 1 clinical study
CG2001 is safe and well-tolerated for treating hair loss in men.
research Transient treatment of pregnant Merino ewes with modulators of cortisol biosynthesis coinciding with primary wool follicle initiation alters lifetime wool growth
Altering maternal cortisol during pregnancy can improve wool growth in Merino sheep.
research A decade of progress in androgenetic alopecia management: Emerging therapies and multimodal strategies
Androgenetic alopecia treatments are becoming more personalized and include new therapies like topical antiandrogens and regenerative strategies.
research Natural bioactive compounds as potential sources for alleviation and treatment of androgenetic alopecia: A research advance
Natural compounds from Chinese herbs may safely promote hair growth and treat common hair loss.
research Novel azaandrostane derivatives for the synthesis of 17β‐(N‐tert‐butyl carbamoyl)‐4‐aza‐5α‐androst‐1‐ene‐3‐one
A new method to make finasteride for hair loss treatment was developed.
research Polynucleotides as a novel therapeutic approach in androgenetic alopecia: an analysis of effectiveness and safety
Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.
research Minimally Invasive Non-Surgical Therapies for Androgenetic Alopecia: A Narrative Review of Clinical Evidence for Regenerative and Locally Acting Antiandrogen Treatments
Platelet-rich plasma, microneedling with minoxidil, and topical finasteride are promising treatments for hair loss.