352 citations
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August 2003 in “Proceedings of the National Academy of Sciences” Nestin is found in hair follicle progenitor cells, linking them to neural stem cells.
5 citations
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February 2014 in “PloS one” Eyelid cells share signaling components but differ in pathway activity.
34 citations
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August 2016 in “Scientific Reports” Blocking TGFβ-RI signaling enhances surface ectoderm differentiation from human stem cells.
33 citations
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August 2000 in “Experimental Cell Research”
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
October 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Small changes in cell division and differentiation can activate blood progenitors.
16 citations
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February 2013 in “Molecular Medicine Reports” CD34+ cells from fat tissue help form hair follicles and blood vessels in skin.
January 2009 in “China Practical Medicine” Certain genes help dermal papillae cells in hair follicles grow and group together.
13 citations
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September 2016 in “Journal of Cellular Biochemistry” Low oxygen levels help hair follicle stem cells turn into heart muscle cells faster.
87 citations
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February 2000 in “Journal of Investigative Dermatology” Stem cells in developing hair follicles move to specific areas as they mature.
1 citations
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March 2022 in “Journal of biological chemistry/The Journal of biological chemistry” Removing a specific gene in certain skin cells causes hair loss in mice by disrupting hair follicle development.
22 citations
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August 1999 in “Mechanisms of Development” Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
Alopecia areata is reversible because hair follicles can regenerate due to stem cells.
387 citations
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November 2003 in “Journal of Investigative Dermatology” The K15 promoter effectively targets stem cells in the hair follicle bulge.
1 citations
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November 2020 in “Biochemical Society transactions” Different types of skin stem cells can change and adapt, which is important for developing new treatments.
Epimorphin helps shape and develop epithelial cells, like those in hair follicles.
24 citations
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April 2012 in “Developmental Biology” Dermal papillae cells, important for hair growth, come from multiple cell lines and can be formed by skin cells, regardless of their origin or hair cycle phase. These cells rarely divide, but their ability to shape tissue may contribute to their efficiency in inducing hair growth.
97 citations
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December 2017 in “Frontiers in Cell and Developmental Biology” Human periapical cyst stem cells could be a promising source for regenerative medicine.
April 2018 in “Journal of Investigative Dermatology” Hair follicle stem cells can change their role to ensure proper hair development.
January 2003 in “Zhonghua shaoshang zazhi” Murine fetal epidermal stem cells can help regenerate hair follicles.
1 citations
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January 2021 CD4+ skin cells may be precursors to basal cell carcinoma.
15 citations
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June 2019 in “eLife” Activin A and follistatin control when hair cells develop in mouse ears.
April 2024 in “The journal of investigative dermatology/Journal of investigative dermatology” ASH2L is essential for skin and hair development.
27 citations
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August 2013 in “Cell Proliferation” Understanding tooth development pathways may help regenerate teeth and treat dental issues.
1 citations
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January 2012 in “International journal of trichology” Sheep hair follicle cells can grow a lot but need the dermal papilla to do so.
7 citations
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October 2018 in “BMC genomics” Key genes can rewire networks, changing skin appendage types.
January 2024 in “Wiadomości Lekarskie” Ancient immune and signaling pathways still regulate blood cell development.
Reprogramming adult fibroblasts may enable scar-free healing.
130 citations
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February 2005 in “Proceedings of the National Academy of Sciences” Corneal cells can transform into skin and hair cells through specific signals.
October 2021 in “Journal of Investigative Dermatology” The study concludes that as skin matures from infancy to childhood, there are major changes in cell differentiation, stemness, and growth, leading to a stronger skin barrier in older children.