58 citations
,
November 2018 in “Cochrane library” Oral isotretinoin may slightly improve acne but increases the risk of side effects like dry lips and skin; more research is needed to understand its full risks and benefits.
53 citations
,
July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” Testosterone boosts red blood cell production and changes iron metabolism without needing dihydrotestosterone.
42 citations
,
July 2021 in “Frontiers in Medicine” Proxalutamide significantly lowered hospital admissions for male COVID-19 patients compared to a placebo.
39 citations
,
November 2021 in “Clinical Endocrinology” Testosterone replacement is recommended for men with low testosterone levels and symptoms of hypogonadism.
29 citations
,
October 2020 in “eLife” Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
29 citations
,
March 2010 in “Cancer epidemiology” Men who start losing hair at age 30 may have a lower risk of prostate cancer.
21 citations
,
January 2017 in “MethodsX” Methanol is better than isopropanol for washing grizzly bear hair to measure cortisol.
19 citations
,
December 2021 in “Endocrine Reviews” There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.
19 citations
,
January 2019 in “International Journal of Trichology” Indian dermatologists recommend treating common hair loss with a balanced diet, stress reduction, mild shampoos, and sometimes minoxidil and supplements.
18 citations
,
January 2020 in “Indian Dermatology Online Journal” Platelet-rich plasma shows potential for hair loss and skin rejuvenation but needs more research for widespread use.
13 citations
,
May 2006 in “Annals of Saudi Medicine” Generic drug inserts in Saudi Arabia often have inaccurate information, needing better regulation and quality control.
12 citations
,
July 2019 in “The Aging Male” Men in the U.S. have more health issues, higher death rates from various diseases, lower life expectancy, and are less likely to seek healthcare.
11 citations
,
October 2021 in “Journal of The European Academy of Dermatology and Venereology” Topical finasteride is an effective and safer treatment for male hair loss.
7 citations
,
April 2008 in “British Journal of Clinical Pharmacology” Stronger regulation and collaboration are needed to ensure online pharmacies are safe and legitimate.
4 citations
,
July 2018 in “Molecules” Gene expression in milk cells and blood can help detect illegal rbST use in cows.
4 citations
,
March 2018 in “Systems biology in reproductive medicine” Men born very underweight had higher estrogen levels but normal reproduction compared to normal birth weight men.
4 citations
,
October 2022 in “American journal of physiology. Heart and circulatory physiology” Higher DHT levels are linked to worse heart changes in severe aortic valve stenosis patients.
2 citations
,
September 2020 Long-term high testosterone levels can improve bone density and reduce body fat but may increase the risk of prostate cancer and high blood pressure.
1 citations
,
September 2023 in “Molecules (Basel. Online)” Plant sterols have health benefits like lowering cholesterol, but more research is needed to understand their effects and improve their extraction and sustainability.
1 citations
,
January 2022 in “Springer eBooks”
March 2026 in “Biomedicines” New treatments like biologics and JAK inhibitors show promise for severe scalp inflammation when traditional methods fail.
February 2026 in “American Journal of Clinical Dermatology” Spironolactone is effective for treating female hair loss, with new treatments like clascoterone showing promise.
January 2026 in “International Journal of Molecular Sciences” Lifestyle changes and environmental strategies can help address declining testosterone levels.
December 2025 in “Neurobiology of Stress” People who recently attempted suicide during depression showed signs of adrenal fatigue, but had higher DHEA levels around the attempt time.
July 2025 in “American Journal of Clinical Dermatology” Alopecia treatments like 5α-reductase inhibitors and spironolactone are safe for breast cancer patients and high-risk women.
August 2024 in “The Journal of Urology” The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.
May 2023 in “IntechOpen eBooks” More research is needed to understand how testosterone is maintained in adult males.
February 2023 in “IntechOpen eBooks” Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.
November 2022 in “The Journal of Clinical Endocrinology and Metabolism” Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.
November 2022 in “Orphanet Journal of Rare Diseases” Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.