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research UT-018 Accelerates Wound Repair and Hair Follicle Regeneration in Murine Models

1 citations , May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)”

UT-018, a stem cell chemoattractant formulation, has shown significant regenerative effects in murine models, accelerating wound repair and promoting hair follicle regeneration. The topical application of UT-018 led to faster wound closure, improved tissue formation, better collagen organization, increased fibroblast activity, and enhanced blood vessel formation in the skin. In hair growth studies, UT-018 increased follicular density, promoted deeper follicle penetration, and induced the transition to the anagen phase, which is the active growth phase of hair. These effects are linked to strong intracellular cAMP generation and β-catenin phosphorylation, indicating GPCR-mediated regenerative signaling.

Clinical Study on the Efficacy and Tolerability of an Oral Supplement Based on Arginine, L-Cystine, Zinc and B6 Vitamin (Cystiphane) in Patients With Telogen Effluvium

research Clinical study on the efficacy and tolerability of an oral supplement based on arginine, l-cystine, zinc and B6 vitamin (Cystiphane®) in patients with telogen effluvium

June 2023 in “Italian journal of dermatology and venereology”

The oral supplement improved hair loss in patients with telogen effluvium.

research Ritlecitinib: Efficacy of a Novel Therapy for Severe Alopecia Areata in Patients Aged 12 Years and Older

December 2025 in “Actas Dermo-Sifiliográficas”

Ritlecitinib is effective and safe for treating severe alopecia areata in people aged 12 and older.

Cyproterone and Finasteride Treatment in a 74-Year-Old Man with Hypersexuality

research Cyproterone/finasteride

July 2016 in “Reactions Weekly”

Cyproterone and finasteride reduced hypersexuality but caused serious side effects.

research A Sensitive Assay for the Enzyme Activity in Hair Follicles and Epidermis that Catalyses the Peptidyl-Arginine-Citrulline Post-translational Modification

3 citations , April 2015 in “Current problems in dermatology”

A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane-Induced Dystrophy and Redirect Polyunsaturated Fatty Acid Metabolism Toward β-Oxidation

research Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation

19 citations , November 2018 in “Nutrients”

Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.

research L-Ornithine ketoacid-transaminase assay in hair roots of homozygotes and heterozygotes for gyrate atrophy

8 citations , June 1981 in “Clinica Chimica Acta”

Anidulafungin-Induced Alopecia: A Case Report

research Anidulafungin-Induced Alopecia

6 citations , March 2014 in “Annals of Pharmacotherapy”

A woman's hair loss was probably caused by the antifungal drug anidulafungin.

Alpha-1 Adrenergic Receptor Agonist Induced Piloerection Protects Against the Development of Traction Alopecia

research α₁-AR agonist induced piloerection protects against the development of traction alopecia

5 citations , December 2015 in “Dermatologic Therapy”

Using a certain drug on the skin can help prevent hair loss caused by pulling on the hair.

research Comparative Studies on Polyamine Levels in Plasma and Urine of Androgenic Alopecia Patients Treated with Finasteride for a Period of Three Years

January 2020 in “International Journal of Applied Biology and P”

Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.

research Amaranthus Extract Promotes Healthy Follicles and Anagen Hair Density-A Randomized Placebo-Controlled, Double-Blinded Study.

October 2025 in “PubMed”

Amaranthus extract cream safely boosts hair growth in men with hair loss.

research Efficacy and safety of a new formulation kit (shampoo + lotion) containing anti‐inflammatory and antioxidant agents to treat hair loss

8 citations , March 2020 in “Dermatologic Therapy”

The new hair loss treatment kit was safe and improved hair growth without any adverse effects.

Phosphatidic Acid Has Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

research Phosphatidic Acid Has a Potential to Promote Hair Growth In Vitro and In Vivo, and Activates Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase in Hair Epithelial Cells

46 citations , August 2003 in “The journal of investigative dermatology/Journal of investigative dermatology”

Phosphatidic acid may help hair grow by affecting cell growth pathways.

research Identification of neprilysin as a potential target of arteannuin using computational drug repositioning

January 2017 in “Brazilian Journal of Pharmaceutical Sciences”

Arteannuin might work against cancer and Alzheimer's by targeting neprilysin.

research Low-Dose Systemic Methotrexate Therapy for Recalcitrant Alopecia Areata

14 citations , January 2017 in “Annals of Dermatology”

Low-dose methotrexate effectively regrows hair in many alopecia areata patients but can cause some side effects.

research 5-Bromo-2′-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice

August 2016 in “Journal of Dermatology”

A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.

research Nitrogen‐Boosted H ₂ O ₂ Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

November 2025 in “Advanced Science”

A new nanozyme using EGCG and L-arginine boosts hair growth by safely increasing beneficial oxidative stress.

research [Low dosage retinol and L-cystine combination improve alopecia of the diffuse type following long-term oral administration].

16 citations , August 1989 in “PubMed”

Retinol and L-cystine improve diffuse hair loss without side effects.

research Treatment of actinic cheilitis with ingenol mebutate gel: Experience in four patients

May 2015 in “Journal of The American Academy of Dermatology”

Finasteride for hair loss in young men increases the risk of sexual dysfunction.

research The state‐of‐the‐art in the management of androgenetic alopecia: A review of new therapies and treatment algorithms

1 citations , July 2022 in “JEADV Clinical Practice”

New and existing treatments for hair loss show promise, with some being more effective for men and others for women.

research Most recent findings of curative drugs for lower urinary tract symptoms in clinical practice

January 2019 in “Nihon Yakuri Gakkai nenkai yoshishu”

Current treatments for lower urinary tract symptoms include α1-blockers, 5ARIs, PDE5 inhibitors, anticholinergic agents, and β3-adrenergic receptor agonists.

research 41701 Efficacy of the Oral JAK1/JAK2 Inhibitor CTP-543 (Deuruxolitinib) in Adult Patients with Moderate to Severe Alopecia Areata: Results from the Multinational Double-Blind, Placebo-Controlled THRIVE-AA1 Phase 3 Trial

2 citations , September 2023 in “Journal of the American Academy of Dermatology”

CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.

research Structural Requirements of Minoxidil Analogs for Enhancing Lysyl Hydroxylase Inhibitory Activity

April 2012 in “KSBB Journal”

Minoxidil analogs can be improved for hair growth inhibition by modifying specific parts of their structure.

research Cyproterone is effective for androgenetic alopecia in women

December 1989 in “Inpharma (Balgowlah)”

Cyproterone helps women with hair loss caused by genetics. More research is needed to confirm the best dose.

research 269 The PPAR-γ modulator, N-acetyl-GED, protects from epithelial-mesenchymal-transition to human hair follicles: Potential relevance for scarring alopecia

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.

research Loose anagen hair syndrome in children of Upper Egypt

12 citations , June 2009 in “Journal of Cosmetic Dermatology”

Loose Anagen Hair syndrome occurs in dark-skinned children and often improves on its own.

research Ruxolitinib 1.5% Topical Cream for the Treatment of Pediatric Alopecia Areata

4 citations , April 2024 in “Journal of Drugs in Dermatology”

Ruxolitinib cream may help treat severe hair loss in children.

research A new combination of molecules for the treatment of androgenetic alopecia and telogen effluvium: a double-blind randomized, monocentric, placebo-controlled study

1 citations , January 2022 in “Italian journal of dermatology and venereology”

The combination of arginine and zinc reduces hair loss and increases hair growth effectively.

research Efficacy and safety of ritlecitinib in adolescents with alopecia areata: Results from the ALLEGRO phase 2b/3 randomized, double‐blind, placebo‐controlled trial

48 citations , July 2023 in “Pediatric Dermatology”

Ritlecitinib effectively regrows hair in adolescents with alopecia areata and is safe.

research Retinoids - new uses and new synthetic agents

January 1988 in “Inpharma (Balgowlah)”

New retinoids are effective for various skin conditions and are being developed to have fewer side effects.

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