research Steroid sulfatase inhibitors
Steroid sulfatase inhibitors could help treat hormone-related disorders and cancers.
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research Safety of Alopecia Treatments in Patients with Breast Cancer and High-Risk Women: A Review
Alopecia treatments like 5α-reductase inhibitors and spironolactone are safe for breast cancer patients and high-risk women.
research Efficacy and safety of oral spironolactone for female pattern hair loss in premenopausal women: a randomized, double-blind, placebo-controlled, parallel-group pilot study
Oral spironolactone effectively promotes hair growth in premenopausal women but may cause irregular menstruation.
research Estrogen deprivation effects of endocrine therapy in breast cancer patients: Incidence, management and outcome
Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
research Finasteride와 저용량 Dutasteride 병용요법으로 호전된 안드로겐성 탈모증 1예
Combining low-dose dutasteride with finasteride improved a man's hair loss.
research AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells
AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.
research A Prospective Randomized Trial Comparing Low Dose Flutamide, Finasteride, Ketoconazole, and Cyproterone Acetate-Estrogen Regimens in the Treatment of Hirsutism
All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.
research Treatment of androgenic disorders in women: acne, hirsutism, and alopecia
Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.
research Effect of finasteride 5 mg (Proscar) on acne and alopecia in female patients with normal serum levels of free testosterone
Finasteride improves acne and hair loss in women with normal testosterone.
research New Synthesis of Finasteride
A new method to make Finasteride is more cost-effective and yields 16%.
research Expression and Activity Assay of Human Steroid 5 Alpha-Reductase Type II in CHO Cells
Finasteride effectively inhibits the enzyme steroid 5 alpha-reductase II.
research IP28-24 RISK OF ERECTILE DYSFUNCTION AMONG REPRODUCTIVE-AGED MEN FOLLOWING LOW-DOSE FINASTERIDE USE FOR ANDROGENETIC ALOPECIA: A PROPENSITY-MATCHED COHORT STUDY
Low-dose finasteride may increase erectile dysfunction risk over time.
research 11 Treatment of hirsutism and acne with cyproterone acetate
Cyproterone acetate is effective for treating hirsutism and acne but less so for hair loss, with side effects similar to birth control pills.
research Clinical and hormonal effects of the 5 alpha-reductase inhibitor finasteride in idiopathic hirsutism
research In vivo and in vitro effect of novel 4,16-pregnadiene-6,20-dione derivatives, as 5α-reductase inhibitors
The new compounds may be more effective and cheaper than current treatments for conditions like baldness.
research Androgenetic alopecia
research Androgenetic alopecia
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Dutasteride: a review of current data on a novel dual inhibitor of 5alpha reductase.
Dutasteride effectively treats enlarged prostate with manageable side effects.
research Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia
A new topical treatment for hair loss shows promise by targeting androgen receptors.
research Male Androgenetic Alopecia : Response To Finasteride
Finasteride is a safe and effective treatment for male hair loss.
research Testosterone Reduces Tight Junction Complexity and Down-regulates Expression of Claudin-4 and Occludin in the Endometrium in Ovariectomized, Sex-steroid Replacement Rats
Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
research Multi-target evaluation of Korean herbal compounds against the SRD5A2 / AR / beta-catenin axis for androgenetic alopecia: Boltz-2 cofold, ChEMBL-anchored ranking, ADMET-AI 107-endpoint safety panel, and pilosebaceous single-cell atlas-constrained prioritization of Saponin Re, Emodin, and Biochanin A
Biochanin A from soy is a promising and safe candidate for treating hair loss.
research Compatibility of 17-α-Estradiol, Betamethasone, Finasteride, Melatonin, Prednicarbate, and Spironolactone in TrichoFoam™ - a Foaming Vehicle for Personalized Alopecia Treatments.
TrichoFoam™ effectively delivers multiple hair loss treatments, maintaining their stability and effectiveness.
research Insights From Liquid Chromatography-Mass Spectrometry-Measured Androgens in Indian Women With Polycystic Ovary Syndrome
Androstenedione is better than testosterone for diagnosing PCOS in Indian women.
research Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone.
GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.
research The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites
Synthetic 19-norprogestins promote bone cell growth and function through their non-phenolic metabolites.
research Topical Estrogen Therapy for Androgenetic Alopecia in Menopausal Females
Topical estrogen helps hair growth in menopausal women with no major side effects.
research Visualising Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research 6 Peripheral androgens and the role of androstanediol glucuronide
Androstanediol glucuronide is a reliable marker for hirsutism in women.