research Efectos de la alteración de los niveles de allopregnanolona durante periodos críticos del neurodesarrollo en la vulnerabilidad al consumo de alcohol
Early NAS level changes affect alcohol consumption vulnerability.
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research Glossary
research The pathogenesis of alopecia areata
Alopecia areata is an autoimmune disease affecting hair follicles and may harm heart health.
research Lab Quality Management and Methodology
Men with early balding should be checked for metabolic syndrome, as there's a link between the two.
research Prostate cancer risk and recurrence: the role of nutrition and clinical aspects
Higher cholesterol levels increase aggressive prostate cancer risk.
research Edthnopharmacological Review of Medicinal Plants for the Treatment of Alopecia
Various medicinal plants like Polygonum multiflorum, Red ginseng extract, and Zizyphus jujuba can potentially treat hair loss, offering benefits like low cost and multiple ways of working. Other effective natural substances include Pygeum africanum, Seneroa, Urtica dioica, and more.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.
research Approach to the Management of Patients With Hidradenitis Suppurativa: A Consensus Document
The consensus document recommends a comprehensive treatment plan for Hidradenitis Suppurativa, including various medications, surgery, lifestyle changes, and the need for more research and resources.
research Fine mapping of the human AR/EDA2R locus in androgenetic alopecia
Genetic marker rs12558842 strongly linked to male hair loss.
research Human platelet lysate versus minoxidil stimulates hair growth by activating anagen promoting signaling pathways
Both human platelet lysate and minoxidil can promote hair growth, but they affect different genes and cell survival rates.
research Next-Gen Therapeutics for Skin Cancer: Nutraceuticals
Certain spices may help prevent and treat skin cancer, but more human trials are needed.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research The hydroxypropyl‐β‐cyclodextrin‐minoxidil inclusion complex improves the cardiovascular and proliferative adverse effects of minoxidil in male rats: Implications in the treatment of alopecia
A new gel form of minoxidil is equally effective for hair growth and safer for the heart and other organs than the traditional solution.
research Endocrinologia e Medicina Estética Ed. X
A comprehensive, personalized approach is needed for treating female pattern hair loss and obesity, involving multiple medical disciplines and lifestyle changes.
research All ABSTRACT
Personalized, minimally invasive treatments improve urology outcomes.
research The Role of Hormonal Imbalances in Amenorrhea
Hormonal imbalances are a key cause of missed menstrual periods in women.
research Cultural evolution as a possible triggering or causative factor of common baldness
Certain cultural hair practices might cause baldness by affecting natural hair oils and stem cell delivery to hair follicles.
research Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice
A mild botulinum toxin injection improved sperm production and movement in aging mice.
research Mechanistic perspectives on the dermatologic potential of topical metformin: A scoping review
Topical metformin shows promise for skin treatments but needs more testing for safety and effectiveness.
research Androgenetic alopecia risk in allergic rhinitis: A cohort study of immune and antihistamine effects
Allergic rhinitis increases hair loss risk, but antihistamines can reduce it.
research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study
Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.
![Activity of 17β-(N-Alkyl/Arylformamido) and 17β-[(N-Alkyl/Aryl) Alkyl/Arylamido]-4-Methyl-4-Aza-5α-Androstan-3-Ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear](/images/research/861159f1-7bd4-420c-a16b-4829458efe68/small/15592.jpg)
research Activity of 17β-(N-Alkyl/arylformamido) and 17β-[(N-Alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5α-androstan-3-ones as 5α-Reductase Inhibitors in the Hamster Flank Organ and Ear11The research has been supported by Endorecherche that is seeking patent protection for the new compounds. F. Labrie is President of Endorecherche.
The compounds tested could potentially treat hair loss and alopecia.
research Inhibition of 5α-reductase attenuates behavioral effects of D1-, but not D2-like receptor agonists in C57BL/6 mice
Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.
research Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells
Ishophloroglucin A from Ishige okamurae may be a natural alternative for treating hair loss by inhibiting 5α-reductase and promoting hair growth.
research A systematic review of antiandrogens and feminization in transgender women
Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
research Diagnosis, Pathogenesis and Management of Polycystic Ovary Syndrome
Lifestyle changes and insulin-sensitizing drugs are effective for managing PCOS.
research Randomized Placebo-Controlled Clinical Trial of Dutasteride for Reducing Heavy Drinking in Men
Dutasteride helps reduce heavy drinking, especially for those who drink to cope.
research Perifollicular Inflammation and Fibrosis in Androgenetic Alopecia: Implications for Diagnosis and Treatment - A Comparative Histopathologic and Clinical Study with Normal-Appearing Scalp
Early biopsy and targeting inflammation can improve treatment for hair loss in androgenetic alopecia.
research Early Antiandrogen Therapy With Dutasteride Reduces Viral Shedding, Inflammatory Responses, and Time-to-Remission in Males With COVID-19: A Randomized, Double-Blind, Placebo-Controlled Interventional Trial (EAT-DUTA AndroCoV Trial – Biochemical)
Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.
research Understanding, recognizing, and managing toxicities of targeted anticancer therapies
Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.