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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Vitamins B3, B6, C, and iron intake affect hormone levels in women with certain types of PCOS.

Certain gene variants are linked to severe acne, especially in males.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Longer GGN repeats in the androgen receptor gene are linked to polycystic ovary syndrome.

PCOS involves high 11-oxygenated androgens and BPA may worsen it, while IH is not inflammatory.

The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.

Prenatal and postnatal environments both affect PCOS development and gut microbiota in mice.

Low androgen levels reduce nitric oxide production in rat penile cells.

Androgen deprivation therapy might help prevent severe COVID-19, but more research is needed.

Fewer GGC sequences in the androgen receptor gene improve finasteride treatment for hair loss.

Early hormones shape sex-specific differences in rat glands.

24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.

AR gene variations don't affect aging markers in men.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

Hormonal status from androgen deprivation therapy may affect COVID-19 severity in men.

Researchers developed reliable models to predict how well certain compounds bind to androgen receptors, emphasizing the importance of atomic electronegativity.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

Higher DHEA-S levels in hirsute females affect hair growth phases.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Androgens affect bone and fat cell development differently based on the cells' embryonic origin.

Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.

Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

Certain gene variations are linked to higher male hormone levels in Chinese women with PCOS and insulin resistance.

Masculinization in affected individuals occurs gradually after puberty due to hormone changes.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

Hormones, especially androgens, affect hair growth and can cause hair loss or excess hair in both men and women.