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Potential compounds may inhibit hair loss by targeting a non-androgen pathway.

Potential compounds may inhibit hair loss by targeting a non-androgen pathway.

Human keratinocytes do not naturally respond to androgens.

New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.

Antiandrogens might help prevent or treat COVID-19 by blocking the virus's entry into cells.

New biological pathways and potential treatment targets for male pattern baldness were identified.

Lowering testosterone speeds up wound healing in male mice.

Enzalutamide, a prostate cancer drug, may help prevent COVID-19 by blocking the virus from entering lung cells.

Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.

New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.

Androgen receptors play a key role in male development and prostate cancer, with treatments targeting androgen action.

Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgen receptors in the brain affect metabolism and reproduction differently in males and females, and may help manage PCOS symptoms in females.

ERG increases SOX9, promoting prostate cancer growth and invasion.

MitoQ helps protect hair cells from damage in hair loss by boosting a protective enzyme.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Individuals with male pseudohermaphroditism often do better raised as females with early surgery.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.

High levels of androgens can cause skin issues like acne, hair loss, and excessive hair growth.

Extracellular vesicles and androgen receptors may help identify prostate cancer resistance and reduce SARS-CoV-2 infection.

New drugs and therapies targeting specific pathways show promise in treating advanced prostate cancer.

Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.

5 alpha-reductase inhibitors, like finasteride, are used to treat conditions like prostate issues and skin disorders.

PROTACs show promise for cancer treatment, but designing them effectively is challenging.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.